Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 5110540..5111979 Replicon chromosome
Accession NZ_CP014158
Organism Pseudomonas citronellolis strain P3B5

Toxin (Protein)


Gene name - Uniprot ID W5IXK4
Locus tag PcP3B5_RS22235 Protein ID WP_009620564.1
Coordinates 5111410..5111979 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A127MY28
Locus tag PcP3B5_RS22230 Protein ID WP_061562414.1
Coordinates 5110540..5111400 (-) Length 287 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PcP3B5_RS22210 5105829..5106773 + 945 WP_043271076.1 bile acid:sodium symporter family protein -
PcP3B5_RS22215 5106916..5107230 + 315 WP_009620556.1 quaternary ammonium compound efflux SMR transporter SugE -
PcP3B5_RS22220 5107422..5107631 + 210 WP_009620558.1 cold-shock protein -
PcP3B5_RS22225 5107681..5109555 - 1875 WP_061562413.1 MFS transporter -
PcP3B5_RS22230 5110540..5111400 - 861 WP_061562414.1 AraC family transcriptional regulator Antitoxin
PcP3B5_RS22235 5111410..5111979 - 570 WP_009620564.1 GNAT family N-acetyltransferase Toxin
PcP3B5_RS22240 5112231..5115707 + 3477 WP_061562415.1 hybrid sensor histidine kinase/response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(20-148)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21064.37 Da        Isoelectric Point: 10.2120

>T60309 WP_009620564.1 NZ_CP014158:c5111979-5111410 [Pseudomonas citronellolis]
MFRPSPITLQRGALRLEPMVEADVPDLVALAEANREALKFMSAPQRPDWYRNSLAEQREGRALPLVVRLGNQLVGTTRFM
DFLPALPACEIGGTWLDAAQHGTGLNASIKYLMLRQAFDNWKMVRVQLKTAASNLRSQRAIEKLGAVREGVLRNHRRLAG
GRLDDSVLYSITDLEWPQVKAALEAGFIG

Download         Length: 570 bp

>T60309 NZ_CP014158:c5111979-5111410 [Pseudomonas citronellolis]
ATGTTCAGACCGTCACCCATCACCCTGCAGCGCGGTGCGCTGCGCCTGGAGCCCATGGTCGAGGCCGACGTGCCGGACCT
GGTGGCTCTGGCCGAGGCCAATCGCGAGGCGCTGAAGTTCATGAGCGCGCCGCAGCGCCCGGACTGGTACCGCAACAGCC
TCGCCGAGCAGCGCGAGGGCCGCGCCCTGCCGCTAGTGGTGCGCCTGGGCAACCAACTGGTGGGCACCACCCGCTTCATG
GACTTCCTCCCGGCGCTGCCGGCCTGCGAGATCGGCGGCACCTGGCTGGATGCGGCGCAGCACGGCACCGGGCTGAACGC
CAGCATCAAGTACCTGATGCTGCGCCAGGCCTTCGACAACTGGAAGATGGTCCGCGTGCAGCTGAAGACCGCCGCCAGCA
ACCTGCGCTCGCAGCGCGCCATCGAGAAGCTCGGCGCGGTGCGCGAGGGCGTGCTGCGCAACCACCGGCGCCTGGCCGGC
GGGCGCCTGGACGACAGCGTTCTCTACAGCATCACCGACCTGGAGTGGCCGCAGGTGAAGGCCGCCCTGGAAGCCGGCTT
CATCGGCTGA

Antitoxin


Download         Length: 287 a.a.        Molecular weight: 31598.98 Da        Isoelectric Point: 9.1317

>AT60309 WP_061562414.1 NZ_CP014158:c5111400-5110540 [Pseudomonas citronellolis]
MPLDSAQGEQTRFWRAQELGGLELLHARFIEQRFAPHVHEGFALVLIEQGAQRFRHRGAEHLAPSGSLVLINPDEVHTGS
KAHEAGWLYRGFYPEIGQVGSVLDELKLGGRGLPTFDASVLHDPELSRAFLHVHRLLESNASSLERQTCWREALLLLFQR
HARVPEARPAGQEPQAVARARELLAARLVEPPSLEELAAAVNLSPFHFARVFRKATGLPPHAWIKQRRLEQARALLKGGC
APASVAAQLGYADQSHLSRQFKQAYGVAPGEYRQACGRSGLPPGNL

Download         Length: 861 bp

>AT60309 NZ_CP014158:c5111400-5110540 [Pseudomonas citronellolis]
ATGCCCCTCGACAGCGCCCAGGGTGAGCAGACGCGCTTCTGGCGGGCCCAGGAACTGGGCGGGCTGGAGTTGCTGCACGC
GCGCTTCATCGAGCAGCGCTTCGCCCCCCACGTCCACGAAGGCTTCGCCCTGGTGCTGATCGAGCAGGGCGCCCAGCGCT
TCCGCCACCGTGGCGCCGAGCACCTGGCGCCCAGCGGCAGCCTGGTGCTGATCAATCCCGACGAGGTCCACACCGGCTCC
AAGGCCCACGAGGCGGGCTGGTTGTACCGGGGGTTCTATCCGGAGATCGGGCAGGTCGGCAGCGTGCTCGACGAGCTGAA
ACTGGGTGGCCGCGGCCTGCCGACCTTCGACGCCAGCGTGTTGCACGATCCCGAGCTGAGCCGTGCCTTCCTGCACGTGC
ACCGCCTGCTGGAATCCAATGCCAGCAGCCTGGAGCGCCAGACCTGCTGGCGCGAGGCATTGCTGTTGCTGTTCCAGCGC
CACGCGCGGGTGCCCGAGGCGCGCCCGGCCGGCCAGGAACCCCAGGCGGTGGCCCGCGCCCGCGAGCTGCTGGCGGCCCG
GCTGGTCGAGCCGCCGTCGCTGGAAGAGCTGGCGGCGGCGGTGAACCTGTCGCCCTTCCACTTCGCCCGGGTGTTCCGCA
AGGCCACCGGCCTGCCGCCCCACGCCTGGATCAAGCAACGCCGCCTGGAACAGGCCCGCGCCCTGCTCAAGGGCGGCTGC
GCGCCGGCCTCGGTGGCGGCGCAACTGGGCTACGCCGACCAGAGCCACCTGAGCCGCCAGTTCAAGCAGGCCTACGGCGT
GGCGCCGGGCGAATACCGCCAGGCCTGCGGACGCTCCGGCCTGCCACCCGGCAACCTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1A5DB72

Antitoxin

Source ID Structure
AlphaFold DB A0A127MY28

References