60298

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 698594..699212 Replicon chromosome
Accession NZ_CP014158
Organism Pseudomonas citronellolis strain P3B5

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag PcP3B5_RS03145 Protein ID WP_203228555.1
Coordinates 698594..698899 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag PcP3B5_RS03150 Protein ID WP_043269347.1
Coordinates 698892..699212 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PcP3B5_RS03120 693605..694330 + 726 WP_009615492.1 alpha/beta fold hydrolase -
PcP3B5_RS03125 694323..695129 + 807 WP_061560555.1 malonyl-ACP O-methyltransferase BioC -
PcP3B5_RS03130 695278..695967 + 690 WP_043269354.1 dethiobiotin synthase -
PcP3B5_RS03135 696034..696261 + 228 WP_009615495.1 hypothetical protein -
PcP3B5_RS03140 696566..698371 + 1806 WP_043269352.1 phenylacyl-CoA dehydrogenase -
PcP3B5_RS03145 698594..698899 + 306 WP_203228555.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PcP3B5_RS03150 698892..699212 + 321 WP_043269347.1 helix-turn-helix domain-containing protein Antitoxin
PcP3B5_RS03155 699382..701178 + 1797 WP_043319190.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -
PcP3B5_RS03160 701397..703175 + 1779 WP_061560556.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(1-89)

Antitoxin

Cro/C1-type helix-turn-helix domain

(30-85)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11190.60 Da        Isoelectric Point: 6.7543

>T60298 WP_203228555.1 NZ_CP014158:698594-698899 [Pseudomonas citronellolis]
MPDDVQDVFGFALHQAQEGGKHPQTKPMKGFSGAGVLEVVEDHDGDTYRAVYTVKLATAVYALHCFQKKSTKGIETPQHD
LELIRKRLKDAQAHAKSVEND

Download         Length: 306 bp

>T60298 NZ_CP014158:698594-698899 [Pseudomonas citronellolis]
ATGCCTGACGATGTCCAGGATGTGTTCGGCTTTGCCCTGCACCAGGCGCAGGAAGGTGGCAAGCACCCCCAGACCAAGCC
GATGAAAGGCTTCTCGGGTGCCGGCGTGCTGGAGGTTGTCGAAGACCATGATGGCGACACCTATCGAGCGGTCTATACGG
TGAAGCTTGCGACGGCGGTCTATGCTCTGCACTGCTTCCAGAAGAAATCGACCAAGGGCATAGAGACTCCGCAGCACGAC
CTGGAGCTGATCAGGAAAAGGCTGAAGGATGCGCAAGCCCATGCGAAGAGCGTAGAGAATGATTGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11579.49 Da        Isoelectric Point: 10.4649

>AT60298 WP_043269347.1 NZ_CP014158:698892-699212 [Pseudomonas citronellolis]
MIEFEEGSGNVYADLGRADAGEMQVKARLASKIGSIIKARHLTQTQAAEILGLPQPKVSDMLRGKFRGISEAKMIDCLAR
LGRDVQIVVKAAPRSRREGRVEVVFA

Download         Length: 321 bp

>AT60298 NZ_CP014158:698892-699212 [Pseudomonas citronellolis]
ATGATTGAGTTCGAAGAAGGCAGCGGCAACGTCTATGCCGACCTCGGCAGGGCCGATGCAGGCGAGATGCAGGTCAAGGC
CAGGCTGGCATCCAAGATCGGTAGCATCATCAAGGCCCGCCACTTGACCCAGACCCAGGCGGCGGAAATCCTCGGGCTCC
CTCAACCCAAGGTTTCCGACATGTTGCGTGGGAAATTCAGAGGCATCAGCGAGGCCAAGATGATCGACTGCCTGGCCCGG
CTCGGACGTGACGTGCAGATCGTGGTCAAGGCCGCACCCCGCTCACGCCGGGAGGGGCGGGTGGAAGTGGTCTTCGCCTG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References