Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2269480..2269627 Replicon chromosome
Accession NZ_CP014154
Organism Klebsiella quasipneumoniae strain HKUOPA4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2269484..2269586 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2269480..2269627 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWV58_RS11235 2264996..2266429 + 1434 WP_053810194.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AWV58_RS11240 2266546..2266785 + 240 WP_002911393.1 YebV family protein -
AWV58_RS11245 2266883..2267074 + 192 WP_002911395.1 YebW family protein -
AWV58_RS11250 2267071..2267724 - 654 WP_053810193.1 protein-serine/threonine phosphatase -
AWV58_RS11255 2267881..2268849 + 969 WP_004203383.1 VirK/YbjX family protein -
AWV58_RS25250 2268953..2269096 + 144 WP_032425946.1 Ecr family regulatory small membrane protein -
- 2269480..2269627 + 148 - - Antitoxin
- 2269484..2269586 - 103 - - Toxin
AWV58_RS11265 2269745..2270083 - 339 WP_002911404.1 YebY family protein -
AWV58_RS11270 2270100..2270969 - 870 WP_004203385.1 copper homeostasis membrane protein CopD -
AWV58_RS11275 2270973..2271347 - 375 WP_053810192.1 CopC domain-containing protein YobA -
AWV58_RS11280 2271460..2271690 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AWV58_RS11285 2271769..2272428 + 660 WP_004203387.1 exodeoxyribonuclease X -
AWV58_RS11290 2272432..2274492 - 2061 WP_053810191.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T60266 NZ_CP014154:c2269586-2269484 [Klebsiella quasipneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 148 bp

>AT60266 NZ_CP014154:2269480-2269627 [Klebsiella quasipneumoniae]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGTCTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References