Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 3612175..3613873 Replicon chromosome
Accession NZ_CP014137
Organism Brenneria goodwinii strain FRB141

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag AWC36_RS16100 Protein ID WP_095834928.1
Coordinates 3612944..3613873 (+) Length 310 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag AWC36_RS16095 Protein ID WP_095834927.1
Coordinates 3612175..3612957 (+) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWC36_RS16075 3608255..3609691 + 1437 Protein_3120 IS1182 family transposase -
AWC36_RS16080 3609923..3610384 - 462 WP_095834924.1 hypothetical protein -
AWC36_RS16090 3610900..3611832 + 933 WP_095834926.1 HrgA protein -
AWC36_RS16095 3612175..3612957 + 783 WP_095834927.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
AWC36_RS16100 3612944..3613873 + 930 WP_095834928.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
AWC36_RS16105 3614418..3614633 + 216 Protein_3125 DUF4102 domain-containing protein -
AWC36_RS24330 3614789..3614974 - 186 WP_183096835.1 hypothetical protein -
AWC36_RS16115 3615068..3616147 - 1080 WP_048636349.1 hypothetical protein -
AWC36_RS16120 3616354..3616455 - 102 WP_183096834.1 IS3 family transposase -
AWC36_RS16125 3616452..3616697 - 246 WP_072065808.1 DDE-type integrase/transposase/recombinase -
AWC36_RS16135 3616875..3617108 + 234 WP_082152979.1 CcdB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3608255..3609499 1244


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-261)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(96-247)


Sequences

Toxin        


Download         Length: 310 a.a.        Molecular weight: 35201.62 Da        Isoelectric Point: 7.0223

>T60253 WP_095834928.1 NZ_CP014137:3612944-3613873 [Brenneria goodwinii]
MDQRDIYARQVKLLMTALPHVARESCFALKGGTAINLFVQNFPRLSVDIDLVYKTFMDRDTDLSAINDALMRITESLNGR
AGITAIRQENKADEKRIIVNTIDAQIKIEVSPVWRGLLLPPTEMPVCEQVEMEYGFTTMNVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPGLTREIFDGFLCYLAGHPRPIAELLAPNWDTARIATLYQQEFSGMTQQETSLESLLSVTTLLPQAL
KSHFTARDRQFLLSYKQNHPDWSLYRYPDIQHLPAIRWKQRNLAALNAKNAAKFTAAVNKLERILEQCF

Download         Length: 930 bp

>T60253 NZ_CP014137:3612944-3613873 [Brenneria goodwinii]
ATGGATCAGCGTGATATTTACGCCCGACAGGTCAAGCTGTTGATGACGGCTCTGCCGCATGTAGCGAGAGAGTCCTGTTT
CGCGCTGAAAGGCGGTACGGCAATTAATTTATTTGTGCAGAATTTCCCTCGTCTATCGGTAGATATCGATCTGGTTTATA
AAACCTTCATGGACCGCGATACCGATCTGTCGGCCATCAATGACGCCTTAATGCGTATTACGGAATCGCTGAACGGCAGA
GCGGGGATCACAGCTATTCGGCAGGAGAATAAAGCCGATGAAAAGCGCATCATCGTTAATACCATTGATGCGCAGATAAA
GATTGAAGTCAGCCCGGTCTGGCGTGGATTGCTGTTGCCACCAACAGAGATGCCAGTATGCGAGCAGGTGGAAATGGAAT
ACGGTTTTACCACCATGAATGTCGTCTCACTGGCGGATCTTTACGGCGGAAAAATCTGCGCCGCACTCGATCGTCAGCAT
CCGCGCGATCTGTTTGACGTACTAAATATGCTGGAGAAACCGGGCCTGACACGCGAGATCTTTGACGGTTTTCTTTGTTA
TCTGGCAGGGCATCCTCGCCCCATAGCCGAACTGCTGGCCCCAAACTGGGACACGGCGCGGATCGCCACGCTGTACCAGC
AGGAATTTTCAGGAATGACGCAGCAAGAGACTTCTCTGGAATCGCTTTTATCAGTAACGACTCTACTGCCGCAGGCGTTG
AAATCTCATTTTACCGCTCGGGATCGTCAGTTCTTACTCAGTTATAAACAGAATCACCCTGACTGGTCGCTGTATCGTTA
TCCTGATATTCAGCATCTCCCGGCCATTCGCTGGAAACAGCGTAACTTAGCGGCGCTGAACGCTAAAAATGCGGCTAAAT
TTACAGCGGCGGTGAACAAGCTTGAGAGGATTCTAGAACAGTGCTTTTGA

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29285.44 Da        Isoelectric Point: 8.3247

>AT60253 WP_095834927.1 NZ_CP014137:3612175-3612957 [Brenneria goodwinii]
MANYLNWLMQNTLPGQVLLQSWLTCNGIDRKLSYRYVQNDWLRRIAHGVYCRTGREPDWVDAVSCLQTQWEKPVRVAGLT
SLALQGHAHYTEPGRPQVWLTLPAYVKLPGWFATFKQSATFVTLYTSGLSADVTPFTTELKIGDRRLMGSCPELAAYEIA
SGVPAQISFEHADTLFQGLNLLSPRKLQALLCASHSIKTNRVVLYLAQRNGHPYFQYLDQHRIETGAGKRQIVSGGWLEP
DYQITVPKEFKPEGVEDGSA

Download         Length: 783 bp

>AT60253 NZ_CP014137:3612175-3612957 [Brenneria goodwinii]
TTGGCAAACTATCTAAACTGGTTGATGCAAAACACCTTACCCGGTCAGGTGCTTCTCCAGTCATGGCTTACCTGCAACGG
CATAGACCGTAAGCTCTCTTACCGCTATGTACAGAACGACTGGCTCAGGCGGATCGCGCATGGCGTTTACTGTCGGACGG
GCCGTGAACCAGACTGGGTCGATGCGGTTTCTTGCCTGCAAACGCAGTGGGAAAAACCGGTGCGGGTGGCAGGGCTGACC
AGTCTTGCGCTACAGGGCCATGCTCACTATACCGAACCGGGCAGGCCGCAGGTCTGGCTCACGCTCCCGGCTTACGTCAA
GCTACCGGGATGGTTCGCCACCTTTAAACAATCCGCCACCTTTGTCACGCTATATACGTCGGGCCTGTCCGCTGATGTAA
CACCATTCACTACAGAACTGAAAATCGGCGATCGGAGATTAATGGGCAGTTGCCCGGAACTTGCCGCGTATGAAATCGCC
AGCGGCGTTCCCGCACAGATCTCGTTTGAACATGCCGACACTCTGTTTCAAGGGCTGAACCTTCTCAGCCCTCGTAAATT
ACAGGCGCTGCTCTGCGCCAGTCATTCGATTAAAACCAATCGGGTGGTGCTCTATCTCGCGCAACGCAACGGACATCCTT
ATTTTCAGTATCTCGATCAACACCGCATAGAAACAGGTGCAGGAAAGCGGCAAATCGTCTCTGGCGGCTGGCTGGAACCG
GATTATCAGATCACTGTCCCCAAGGAATTTAAACCAGAAGGAGTCGAAGATGGATCAGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References