Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 3457798..3458458 | Replicon | chromosome |
Accession | NZ_CP014137 | ||
Organism | Brenneria goodwinii strain FRB141 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | - |
Locus tag | AWC36_RS15350 | Protein ID | WP_048636219.1 |
Coordinates | 3457798..3458211 (-) | Length | 138 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | - |
Locus tag | AWC36_RS15355 | Protein ID | WP_048639667.1 |
Coordinates | 3458192..3458458 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AWC36_RS15330 | 3453211..3454110 | - | 900 | WP_095834857.1 | site-specific tyrosine recombinase XerD | - |
AWC36_RS15335 | 3454492..3455817 | + | 1326 | WP_048636216.1 | MHS family MFS transporter | - |
AWC36_RS15340 | 3456005..3456523 | + | 519 | WP_048636217.1 | flavodoxin FldB | - |
AWC36_RS15345 | 3456618..3457571 | - | 954 | WP_095834858.1 | 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF | - |
AWC36_RS15350 | 3457798..3458211 | - | 414 | WP_048636219.1 | protein YgfX | Toxin |
AWC36_RS15355 | 3458192..3458458 | - | 267 | WP_048639667.1 | FAD assembly factor SdhE | Antitoxin |
AWC36_RS15360 | 3458679..3459665 | + | 987 | WP_095834859.1 | tRNA-modifying protein YgfZ | - |
AWC36_RS15365 | 3459711..3460358 | - | 648 | WP_048636221.1 | hemolysin III family protein | - |
AWC36_RS15370 | 3461052..3461660 | + | 609 | WP_095834860.1 | HD domain-containing protein | - |
AWC36_RS15375 | 3461722..3463029 | - | 1308 | WP_095834861.1 | ABC transporter substrate-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 138 a.a. Molecular weight: 16181.14 Da Isoelectric Point: 11.4874
>T60252 WP_048636219.1 NZ_CP014137:c3458211-3457798 [Brenneria goodwinii]
VAQWQCDLRVSWRMQLFSLVVHGLLVLLILLAPWPDSYTVLWLGLVTLVVFGFIRSQRNIKSRQGEILLHSATQLRWQKQ
EWLIVKRPWMLKNGVLLSLTAMDGKGRQRLWLASDSMGDDEWRHLRQLLLQHKSWAR
VAQWQCDLRVSWRMQLFSLVVHGLLVLLILLAPWPDSYTVLWLGLVTLVVFGFIRSQRNIKSRQGEILLHSATQLRWQKQ
EWLIVKRPWMLKNGVLLSLTAMDGKGRQRLWLASDSMGDDEWRHLRQLLLQHKSWAR
Download Length: 414 bp
>T60252 NZ_CP014137:c3458211-3457798 [Brenneria goodwinii]
GTGGCCCAGTGGCAATGTGATCTGCGCGTTTCCTGGCGCATGCAGCTTTTTTCGCTGGTTGTGCACGGGTTATTGGTGTT
ATTGATACTGCTGGCTCCCTGGCCGGACAGTTATACCGTGTTGTGGCTGGGGCTGGTGACGCTGGTGGTGTTCGGTTTTA
TCCGTAGTCAGCGAAACATCAAATCCCGACAGGGCGAAATTTTATTACATAGCGCAACACAGCTGCGCTGGCAGAAACAG
GAATGGCTGATCGTCAAACGTCCCTGGATGTTGAAGAATGGCGTTTTGCTATCGCTGACAGCGATGGATGGCAAAGGTCG
ACAGCGCCTGTGGCTGGCGTCGGACAGCATGGGGGATGACGAATGGCGTCATTTGCGCCAACTGCTGTTGCAGCATAAAA
GCTGGGCCAGGTGA
GTGGCCCAGTGGCAATGTGATCTGCGCGTTTCCTGGCGCATGCAGCTTTTTTCGCTGGTTGTGCACGGGTTATTGGTGTT
ATTGATACTGCTGGCTCCCTGGCCGGACAGTTATACCGTGTTGTGGCTGGGGCTGGTGACGCTGGTGGTGTTCGGTTTTA
TCCGTAGTCAGCGAAACATCAAATCCCGACAGGGCGAAATTTTATTACATAGCGCAACACAGCTGCGCTGGCAGAAACAG
GAATGGCTGATCGTCAAACGTCCCTGGATGTTGAAGAATGGCGTTTTGCTATCGCTGACAGCGATGGATGGCAAAGGTCG
ACAGCGCCTGTGGCTGGCGTCGGACAGCATGGGGGATGACGAATGGCGTCATTTGCGCCAACTGCTGTTGCAGCATAAAA
GCTGGGCCAGGTGA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10550.04 Da Isoelectric Point: 5.6037
>AT60252 WP_048639667.1 NZ_CP014137:c3458458-3458192 [Brenneria goodwinii]
MEIDNKSRIHWACRRGMRELDISIMPFFEHDYDALSDDDKRVFVRLLQCDDPDLFNWLMNHGQPQDQDLKRMISLIQTRN
KDRGPVAM
MEIDNKSRIHWACRRGMRELDISIMPFFEHDYDALSDDDKRVFVRLLQCDDPDLFNWLMNHGQPQDQDLKRMISLIQTRN
KDRGPVAM
Download Length: 267 bp
>AT60252 NZ_CP014137:c3458458-3458192 [Brenneria goodwinii]
ATGGAAATCGATAATAAATCACGGATTCATTGGGCATGCCGGCGCGGTATGCGTGAACTGGATATTTCTATCATGCCCTT
TTTTGAGCATGACTATGATGCGTTAAGCGATGATGATAAACGCGTGTTTGTCCGTCTGTTGCAGTGCGACGATCCAGACT
TGTTTAACTGGTTGATGAATCACGGGCAACCGCAAGACCAGGATCTGAAACGTATGATCTCCCTCATCCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCAATGTGA
ATGGAAATCGATAATAAATCACGGATTCATTGGGCATGCCGGCGCGGTATGCGTGAACTGGATATTTCTATCATGCCCTT
TTTTGAGCATGACTATGATGCGTTAAGCGATGATGATAAACGCGTGTTTGTCCGTCTGTTGCAGTGCGACGATCCAGACT
TGTTTAACTGGTTGATGAATCACGGGCAACCGCAAGACCAGGATCTGAAACGTATGATCTCCCTCATCCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCAATGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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