Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3457798..3458458 Replicon chromosome
Accession NZ_CP014137
Organism Brenneria goodwinii strain FRB141

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag AWC36_RS15350 Protein ID WP_048636219.1
Coordinates 3457798..3458211 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag AWC36_RS15355 Protein ID WP_048639667.1
Coordinates 3458192..3458458 (-) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWC36_RS15330 3453211..3454110 - 900 WP_095834857.1 site-specific tyrosine recombinase XerD -
AWC36_RS15335 3454492..3455817 + 1326 WP_048636216.1 MHS family MFS transporter -
AWC36_RS15340 3456005..3456523 + 519 WP_048636217.1 flavodoxin FldB -
AWC36_RS15345 3456618..3457571 - 954 WP_095834858.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
AWC36_RS15350 3457798..3458211 - 414 WP_048636219.1 protein YgfX Toxin
AWC36_RS15355 3458192..3458458 - 267 WP_048639667.1 FAD assembly factor SdhE Antitoxin
AWC36_RS15360 3458679..3459665 + 987 WP_095834859.1 tRNA-modifying protein YgfZ -
AWC36_RS15365 3459711..3460358 - 648 WP_048636221.1 hemolysin III family protein -
AWC36_RS15370 3461052..3461660 + 609 WP_095834860.1 HD domain-containing protein -
AWC36_RS15375 3461722..3463029 - 1308 WP_095834861.1 ABC transporter substrate-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-132)

Antitoxin

(8-79)


Sequences


Toxin        


Download         Length: 138 a.a.        Molecular weight: 16181.14 Da        Isoelectric Point: 11.4874

>T60252 WP_048636219.1 NZ_CP014137:c3458211-3457798 [Brenneria goodwinii]
VAQWQCDLRVSWRMQLFSLVVHGLLVLLILLAPWPDSYTVLWLGLVTLVVFGFIRSQRNIKSRQGEILLHSATQLRWQKQ
EWLIVKRPWMLKNGVLLSLTAMDGKGRQRLWLASDSMGDDEWRHLRQLLLQHKSWAR

Download         Length: 414 bp

>T60252 NZ_CP014137:c3458211-3457798 [Brenneria goodwinii]
GTGGCCCAGTGGCAATGTGATCTGCGCGTTTCCTGGCGCATGCAGCTTTTTTCGCTGGTTGTGCACGGGTTATTGGTGTT
ATTGATACTGCTGGCTCCCTGGCCGGACAGTTATACCGTGTTGTGGCTGGGGCTGGTGACGCTGGTGGTGTTCGGTTTTA
TCCGTAGTCAGCGAAACATCAAATCCCGACAGGGCGAAATTTTATTACATAGCGCAACACAGCTGCGCTGGCAGAAACAG
GAATGGCTGATCGTCAAACGTCCCTGGATGTTGAAGAATGGCGTTTTGCTATCGCTGACAGCGATGGATGGCAAAGGTCG
ACAGCGCCTGTGGCTGGCGTCGGACAGCATGGGGGATGACGAATGGCGTCATTTGCGCCAACTGCTGTTGCAGCATAAAA
GCTGGGCCAGGTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.04 Da        Isoelectric Point: 5.6037

>AT60252 WP_048639667.1 NZ_CP014137:c3458458-3458192 [Brenneria goodwinii]
MEIDNKSRIHWACRRGMRELDISIMPFFEHDYDALSDDDKRVFVRLLQCDDPDLFNWLMNHGQPQDQDLKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT60252 NZ_CP014137:c3458458-3458192 [Brenneria goodwinii]
ATGGAAATCGATAATAAATCACGGATTCATTGGGCATGCCGGCGCGGTATGCGTGAACTGGATATTTCTATCATGCCCTT
TTTTGAGCATGACTATGATGCGTTAAGCGATGATGATAAACGCGTGTTTGTCCGTCTGTTGCAGTGCGACGATCCAGACT
TGTTTAACTGGTTGATGAATCACGGGCAACCGCAAGACCAGGATCTGAAACGTATGATCTCCCTCATCCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCAATGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References