Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 3312439..3313181 Replicon chromosome
Accession NZ_CP014137
Organism Brenneria goodwinii strain FRB141

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag AWC36_RS14730 Protein ID WP_095834791.1
Coordinates 3312439..3312918 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag AWC36_RS14735 Protein ID WP_095834792.1
Coordinates 3312909..3313181 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWC36_RS14720 3308927..3310891 + 1965 WP_048636108.1 transporter substrate-binding domain-containing protein -
AWC36_RS14725 3310881..3312269 + 1389 WP_095834790.1 sigma-54 dependent transcriptional regulator -
AWC36_RS14730 3312439..3312918 - 480 WP_095834791.1 GNAT family N-acetyltransferase Toxin
AWC36_RS14735 3312909..3313181 - 273 WP_095834792.1 DUF1778 domain-containing protein Antitoxin
AWC36_RS14740 3313760..3313887 + 128 Protein_2864 transposase -
AWC36_RS14745 3314163..3315008 + 846 WP_095834793.1 SAM-dependent methyltransferase -
AWC36_RS14750 3315398..3315676 + 279 Protein_2866 SDR family oxidoreductase -
AWC36_RS14755 3315692..3316088 + 397 Protein_2867 VOC family protein -
AWC36_RS14760 3316092..3316460 + 369 WP_095834794.1 saccharopine dehydrogenase NADP-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3301260..3315008 13748


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(25-147)

Antitoxin

Vibrio phage ICP1, Orf50

(3-90)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17555.33 Da        Isoelectric Point: 9.9557

>T60251 WP_095834791.1 NZ_CP014137:c3312918-3312439 [Brenneria goodwinii]
VGITAPELLLPQHAVVDFRSSEPTLDEWLKRKAFKNQTISASRIFVVCESGGNQVVGFYALATGSVQRQSVSGALRRNMP
DPLPVLVLGRLAVDERYHRRGIGARLLKDAVLRSQLVAEQVGTKALLVHALSEEAKAFYLHWGFTPSEIQPSTLLLPLW

Download         Length: 480 bp

>T60251 NZ_CP014137:c3312918-3312439 [Brenneria goodwinii]
GTGGGAATAACGGCACCTGAATTATTATTACCTCAGCATGCCGTTGTTGATTTCCGAAGTTCAGAGCCAACACTGGACGA
ATGGCTGAAGCGTAAAGCATTCAAGAATCAAACCATTAGTGCATCACGAATCTTTGTTGTGTGTGAATCGGGTGGAAATC
AGGTTGTTGGCTTTTACGCGCTGGCAACGGGAAGCGTACAGCGTCAATCTGTATCGGGTGCTTTACGGCGTAACATGCCT
GATCCGCTTCCCGTATTAGTATTGGGGCGTCTGGCGGTGGATGAACGCTATCACCGTCGGGGGATTGGTGCGCGGCTGTT
GAAAGATGCGGTCTTACGTTCTCAGCTGGTTGCTGAACAGGTGGGAACGAAAGCGCTATTAGTTCATGCGCTGTCTGAGG
AGGCAAAGGCTTTTTATCTGCACTGGGGCTTTACGCCCTCGGAAATCCAGCCTAGCACGTTGCTTCTACCGCTCTGGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10263.86 Da        Isoelectric Point: 6.3292

>AT60251 WP_095834792.1 NZ_CP014137:c3313181-3312909 [Brenneria goodwinii]
MRTEAKETPINIRAKSSQRELIDVAAKLLSKSCTDFILEAACREAEKVLLDQRLFLVDKSQFDAFITALEKPVATNERLQ
ALLDRKSPWE

Download         Length: 273 bp

>AT60251 NZ_CP014137:c3313181-3312909 [Brenneria goodwinii]
ATGAGAACAGAAGCGAAAGAGACACCAATCAACATTCGGGCGAAATCATCACAGCGGGAACTGATAGATGTTGCCGCGAA
GCTGCTTTCAAAATCATGTACTGATTTTATCCTTGAAGCGGCATGTCGTGAGGCGGAAAAGGTGCTATTGGATCAACGCT
TGTTTCTGGTTGATAAATCACAATTTGATGCGTTTATTACTGCATTAGAAAAACCCGTCGCAACGAATGAGCGGTTACAG
GCGTTATTAGACAGGAAATCACCGTGGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References