Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 60109..60823 Replicon chromosome
Accession NZ_CP014137
Organism Brenneria goodwinii strain FRB141

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AWC36_RS00285 Protein ID WP_095833254.1
Coordinates 60109..60504 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AWC36_RS00290 Protein ID WP_095833255.1
Coordinates 60494..60823 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWC36_RS00275 57117..58673 - 1557 WP_095833253.1 Tar ligand binding domain-containing protein -
AWC36_RS00280 59310..60002 + 693 WP_095835688.1 glutamine amidotransferase -
AWC36_RS00285 60109..60504 + 396 WP_095833254.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AWC36_RS00290 60494..60823 + 330 WP_095833255.1 helix-turn-helix domain-containing protein Antitoxin
AWC36_RS00295 61244..62071 + 828 WP_048639814.1 nitrogenase iron protein -
AWC36_RS00300 62268..63836 + 1569 WP_048637598.1 nitrogenase iron-iron protein, alpha chain -
AWC36_RS00305 63848..64198 + 351 WP_048637599.1 Fe-only nitrogenase subunit delta -
AWC36_RS00310 64211..65599 + 1389 WP_095833256.1 Fe-only nitrogenase subunit beta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(5-126)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-96)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14884.27 Da        Isoelectric Point: 9.6989

>T60246 WP_095833254.1 NZ_CP014137:60109-60504 [Brenneria goodwinii]
MDLAIYTTKLFDRKMKKEDVTDVDLCQAASEVMNSCFEADLGGGVLKKRLALQSGKSGGARSIIFFKKGSHVFFFDGWRK
KQITKKGAKEIEEDVLNTYKDFAAVFLQYDAAMITRLKKAKQLREVNCDER

Download         Length: 396 bp

>T60246 NZ_CP014137:60109-60504 [Brenneria goodwinii]
ATGGATTTGGCGATATATACAACGAAGCTATTTGACCGGAAAATGAAAAAGGAAGATGTGACTGACGTTGATTTATGTCA
GGCGGCGTCAGAAGTGATGAACAGTTGTTTCGAGGCGGATTTAGGCGGCGGCGTATTAAAAAAACGTCTGGCTCTACAGA
GTGGTAAAAGTGGCGGCGCGAGATCCATCATCTTCTTCAAAAAAGGAAGTCATGTATTTTTTTTCGATGGTTGGAGAAAA
AAACAAATCACCAAGAAAGGCGCAAAAGAGATCGAGGAAGATGTGCTCAACACTTATAAGGATTTCGCAGCAGTTTTTCT
ACAGTATGATGCAGCGATGATAACCAGACTGAAAAAAGCAAAGCAATTAAGAGAGGTAAATTGCGATGAGCGCTAA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12313.19 Da        Isoelectric Point: 9.7742

>AT60246 WP_095833255.1 NZ_CP014137:60494-60823 [Brenneria goodwinii]
MSANLKELQALAQELHEHGAMPDETMSRINARVRSRELRERIARVHVMTGTQIKSMRERYGMSQSTLAYTLGMSVESVSK
WERGEIQPSGPALRILNTIDAKGPEVFML

Download         Length: 330 bp

>AT60246 NZ_CP014137:60494-60823 [Brenneria goodwinii]
ATGAGCGCTAACTTGAAAGAGCTACAGGCACTGGCGCAGGAACTGCATGAGCACGGCGCTATGCCAGACGAAACCATGTC
CCGGATTAATGCACGCGTCAGATCGCGGGAACTTCGTGAGCGCATAGCCAGGGTTCATGTAATGACGGGAACGCAGATTA
AATCCATGCGTGAACGTTACGGCATGTCGCAGTCAACGCTGGCTTACACGTTGGGGATGTCAGTCGAAAGCGTATCAAAG
TGGGAGCGGGGAGAGATTCAGCCCAGCGGTCCGGCATTGCGTATCCTCAACACGATTGACGCCAAAGGCCCTGAAGTTTT
TATGCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References