Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3598721..3599399 Replicon chromosome
Accession NZ_CP014136
Organism Gibbsiella quercinecans strain FRB97

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag AWC35_RS16715 Protein ID WP_095847351.1
Coordinates 3598968..3599399 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag AWC35_RS16710 Protein ID WP_095849067.1
Coordinates 3598721..3598987 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWC35_RS16695 3595924..3596532 - 609 WP_095847348.1 HD domain-containing protein -
AWC35_RS16700 3596727..3597401 + 675 WP_095847349.1 hemolysin III family protein -
AWC35_RS16705 3597443..3598432 - 990 WP_095847350.1 tRNA-modifying protein YgfZ -
AWC35_RS16710 3598721..3598987 + 267 WP_095849067.1 FAD assembly factor SdhE Antitoxin
AWC35_RS16715 3598968..3599399 + 432 WP_095847351.1 hypothetical protein Toxin
AWC35_RS16720 3599421..3599939 - 519 WP_095847352.1 flavodoxin FldB -
AWC35_RS16725 3600008..3600958 + 951 WP_183096689.1 site-specific tyrosine recombinase XerD -
AWC35_RS16730 3600985..3601701 + 717 WP_095847354.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
AWC35_RS16735 3601708..3603441 + 1734 WP_095847355.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-130)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 16987.99 Da        Isoelectric Point: 11.2102

>T60235 WP_095847351.1 NZ_CP014136:3598968-3599399 [Gibbsiella quercinecans]
VAQWRCDVRISWRTQLLSLLLHGVLILLILVSPWPDGYGPVWLVLLTLVVFECIRSQRRIAQCRGELRLQADRHVSWHGK
EWLLVKKPWLQPYGVMLSLRQIQGKKRRRLWLASDSMDKAEWRQLRQRLNFPPAADGEDQWRS

Download         Length: 432 bp

>T60235 NZ_CP014136:3598968-3599399 [Gibbsiella quercinecans]
GTGGCCCAGTGGCGATGTGATGTCCGCATCTCCTGGCGCACCCAGTTACTTTCGCTGCTGTTGCACGGCGTTCTTATCCT
GCTGATTCTGGTTTCGCCTTGGCCGGATGGCTATGGCCCCGTCTGGCTGGTATTGCTGACGCTGGTGGTATTTGAATGTA
TTCGCAGCCAGCGGCGTATCGCGCAATGCCGTGGTGAACTGCGCCTGCAGGCCGATCGGCACGTCAGTTGGCACGGCAAG
GAGTGGCTGTTGGTGAAGAAACCCTGGCTGCAGCCTTATGGGGTTATGCTGTCGCTGCGCCAGATTCAGGGGAAAAAGCG
CCGCCGTTTGTGGTTGGCTTCCGACAGTATGGATAAAGCGGAGTGGCGCCAACTGCGCCAGCGGTTGAATTTCCCGCCGG
CCGCGGATGGTGAAGATCAATGGCGCAGCTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10427.94 Da        Isoelectric Point: 5.0990

>AT60235 WP_095849067.1 NZ_CP014136:3598721-3598987 [Gibbsiella quercinecans]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDTLSDADKALFIRLLESDDPDLFNWLMNHGAPQDAELQRMVRLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT60235 NZ_CP014136:3598721-3598987 [Gibbsiella quercinecans]
ATGGATATTAATAATAAAGCACGTATTCATTGGGCATGCCGCCGTGGGATGCGTGAGCTGGATATATCGATCATGCCGTT
TTTCGAATACGAATACGACACGTTGAGCGATGCGGACAAGGCGCTGTTTATTCGCCTGCTCGAGAGTGATGATCCCGATC
TGTTTAACTGGCTGATGAATCATGGCGCTCCGCAGGATGCTGAACTGCAGAGGATGGTGAGATTGATCCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References