60233

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 2984929..2985592 Replicon chromosome
Accession NZ_CP014136
Organism Gibbsiella quercinecans strain FRB97

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag AWC35_RS14005 Protein ID WP_095846872.1
Coordinates 2985248..2985592 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag AWC35_RS14000 Protein ID WP_095846871.1
Coordinates 2984929..2985246 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWC35_RS13975 2981023..2981391 + 369 WP_095846866.1 diacylglycerol kinase -
AWC35_RS13980 2981526..2982134 + 609 WP_095846867.1 transcriptional repressor LexA -
AWC35_RS13985 2982228..2983577 + 1350 WP_095846868.1 MATE family efflux transporter DinF -
AWC35_RS13990 2983869..2984078 + 210 WP_095846869.1 CsbD family protein -
AWC35_RS13995 2984161..2984670 - 510 WP_095846870.1 zinc uptake transcriptional repressor Zur -
AWC35_RS14000 2984929..2985246 - 318 WP_095846871.1 helix-turn-helix domain-containing protein Antitoxin
AWC35_RS14005 2985248..2985592 - 345 WP_095846872.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AWC35_RS14010 2985958..2987007 + 1050 WP_095846873.1 tRNA dihydrouridine(20/20a) synthase DusA -
AWC35_RS14015 2987165..2987383 + 219 WP_095846874.1 envelope stress response protein PspG -
AWC35_RS14020 2987726..2988709 - 984 WP_095846875.1 quinone oxidoreductase -
AWC35_RS14025 2988822..2990237 + 1416 WP_095846876.1 replicative DNA helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-90)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12414.15 Da        Isoelectric Point: 9.6247

>T60233 WP_095846872.1 NZ_CP014136:c2985592-2985248 [Gibbsiella quercinecans]
MKPLYWVGSSKKDLQSLPEDVQDVFGYALHLAQAGGKHAQAKPLKGFGGAGALEVVEDFFSDTYRAVYTVKFGDAVYVLH
VFQKKSSSGVATPKPDMDKIRERLKAAESHARGA

Download         Length: 345 bp

>T60233 NZ_CP014136:c2985592-2985248 [Gibbsiella quercinecans]
ATGAAGCCACTATATTGGGTTGGCAGCAGCAAGAAAGACCTCCAGTCATTGCCCGAGGATGTACAGGATGTTTTCGGCTA
TGCCCTGCATCTGGCGCAGGCAGGCGGTAAACATGCCCAGGCCAAGCCACTGAAAGGGTTTGGCGGCGCTGGCGCGCTTG
AGGTGGTTGAAGACTTTTTCAGTGATACTTATCGTGCGGTGTATACCGTTAAGTTCGGTGATGCCGTCTATGTTTTGCAC
GTATTCCAGAAAAAGTCTTCATCAGGGGTTGCCACACCGAAACCCGATATGGACAAAATCCGTGAACGGCTGAAAGCCGC
AGAAAGCCATGCCAGAGGAGCATAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11585.47 Da        Isoelectric Point: 10.5502

>AT60233 WP_095846871.1 NZ_CP014136:c2985246-2984929 [Gibbsiella quercinecans]
MSHDIEISSGNVYADIGREDAEEMRVKAQLATTIGNIIKSRRLTQEQAAKLLGMTQPKVSNMLRGQFRGISEAKMLECLT
RLGRDVQIVVGKPRRTPGSLTVVFA

Download         Length: 318 bp

>AT60233 NZ_CP014136:c2985246-2984929 [Gibbsiella quercinecans]
ATGAGCCATGATATTGAAATCAGCAGCGGCAACGTTTATGCCGATATTGGCAGAGAAGACGCAGAGGAAATGCGGGTAAA
AGCCCAGCTTGCCACCACCATTGGCAACATCATTAAAAGCCGTCGCCTGACACAGGAACAAGCTGCAAAACTGCTGGGAA
TGACGCAACCCAAGGTATCTAATATGCTGCGTGGGCAGTTCCGGGGCATCAGTGAAGCCAAAATGCTGGAATGCCTGACC
CGCTTAGGGCGCGATGTGCAAATCGTGGTAGGAAAGCCGCGCCGGACACCGGGCAGCTTGACCGTAGTGTTTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References