60230

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 118540..119063 Replicon chromosome
Accession NZ_CP014134
Organism Vibrio diabolicus strain FDAARGOS_99

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AL468_RS09745 Protein ID WP_104974017.1
Coordinates 118540..118812 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag AL468_RS09750 Protein ID WP_104974018.1
Coordinates 118821..119063 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL468_RS09690 113923..114363 + 441 WP_104974013.1 outer membrane protein assembly factor BamE -
AL468_RS09695 114383..114475 + 93 WP_079856521.1 DUF3265 domain-containing protein -
AL468_RS09705 115055..115531 + 477 WP_104974015.1 DUF2059 domain-containing protein -
AL468_RS09710 115690..116118 + 429 WP_104974016.1 GNAT family N-acetyltransferase -
AL468_RS09715 116150..116242 + 93 WP_005445734.1 DUF3265 domain-containing protein -
AL468_RS09720 116288..117004 + 717 WP_023585735.1 riboflavin synthase -
AL468_RS09725 117019..117111 + 93 Protein_204 DUF3265 domain-containing protein -
AL468_RS09735 117600..117731 + 132 WP_010448870.1 DUF3265 domain-containing protein -
AL468_RS09740 117772..118320 + 549 WP_025502402.1 hypothetical protein -
AL468_RS09745 118540..118812 - 273 WP_104974017.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AL468_RS09750 118821..119063 - 243 WP_104974018.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
AL468_RS09755 119312..120403 + 1092 WP_104974019.1 DUF4935 domain-containing protein -
AL468_RS09760 120431..120523 + 93 WP_072600976.1 DUF3265 domain-containing protein -
AL468_RS09765 120552..120948 + 397 Protein_211 hypothetical protein -
AL468_RS09770 120963..121055 + 93 WP_017821407.1 DUF3265 domain-containing protein -
AL468_RS09775 121088..121582 + 495 WP_104974021.1 GNAT family N-acetyltransferase -
AL468_RS09780 121772..122320 + 549 WP_104974022.1 hypothetical protein -
AL468_RS24975 122358..122450 + 93 WP_072600976.1 DUF3265 domain-containing protein -
AL468_RS09800 123272..123388 + 117 WP_104973885.1 DUF3265 domain-containing protein -
AL468_RS09805 123831..124052 + 222 WP_104974024.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 27819..131637 103818


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-49)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10415.94 Da        Isoelectric Point: 9.6424

>T60230 WP_104974017.1 NZ_CP014134:c118812-118540 [Vibrio diabolicus]
MQKKTYKLSKLAQNHLRKIKSYTVTNFSELQWNNYRDNLLTAFQMLADNPAVGRSCDELYSNGFYFPVGKHTAYFTKEDG
FILIVAILGQ

Download         Length: 273 bp

>T60230 NZ_CP014134:c118812-118540 [Vibrio diabolicus]
ATGCAAAAGAAAACATATAAGCTAAGTAAATTAGCTCAAAACCATTTACGTAAGATCAAAAGCTACACCGTTACAAACTT
TTCAGAATTACAATGGAATAACTACAGGGACAACCTACTTACTGCTTTTCAAATGCTTGCTGACAACCCTGCGGTTGGAA
GAAGCTGTGATGAGTTGTACTCAAATGGCTTCTACTTCCCCGTTGGTAAGCACACAGCCTACTTTACCAAAGAAGACGGT
TTTATTCTGATCGTCGCCATTCTTGGTCAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9021.31 Da        Isoelectric Point: 5.1297

>AT60230 WP_104974018.1 NZ_CP014134:c119063-118821 [Vibrio diabolicus]
MQTLTANDAKRNFGELLLSAQREPVKISKNSKDAVVVMSIRDYEELEAMKADYIKHCFETAKEDLAKGNVVDGETFLKNL

Download         Length: 243 bp

>AT60230 NZ_CP014134:c119063-118821 [Vibrio diabolicus]
ATGCAAACATTAACAGCAAATGACGCCAAACGTAACTTTGGTGAACTACTTCTGAGCGCTCAACGAGAGCCAGTTAAAAT
CAGCAAAAACAGCAAAGATGCTGTCGTTGTTATGTCCATTAGAGATTACGAAGAACTTGAAGCGATGAAAGCTGATTACA
TTAAACATTGCTTTGAGACTGCCAAAGAGGACCTAGCAAAAGGTAATGTAGTTGATGGCGAAACATTCTTGAAGAACCTG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References