Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 1957689..1958273 Replicon chromosome
Accession NZ_CP014129
Organism Pantoea vagans strain FDAARGOS_160

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag AL522_RS13050 Protein ID WP_061062307.1
Coordinates 1957689..1958024 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag AL522_RS13055 Protein ID WP_033782896.1
Coordinates 1958025..1958273 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL522_RS13040 1953725..1956343 + 2619 WP_061062305.1 nitrate reductase -
AL522_RS13045 1956343..1957224 + 882 WP_061062306.1 uroporphyrinogen-III C-methyltransferase -
AL522_RS13050 1957689..1958024 - 336 WP_061062307.1 endoribonuclease MazF Toxin
AL522_RS13055 1958025..1958273 - 249 WP_033782896.1 type II toxin-antitoxin system antitoxin MazE Antitoxin
AL522_RS13060 1958422..1959234 - 813 WP_033782898.1 DeoR/GlpR family DNA-binding transcription regulator -
AL522_RS13065 1959587..1960384 + 798 WP_061062308.1 D-threitol dehydrogenase -
AL522_RS13070 1960440..1961375 + 936 WP_061062309.1 D-ribose ABC transporter substrate-binding protein -
AL522_RS13075 1961421..1962032 + 612 WP_061062310.1 DUF2291 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(5-111)

Antitoxin

Antitoxin PemI-like

(3-82)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 11986.95 Da        Isoelectric Point: 9.2256

>T60222 WP_061062307.1 NZ_CP014129:c1958024-1957689 [Pantoea vagans]
MVSRFVPEAGDIIWVDFDPTKGSEQAGHRPAVVLSPFAYNNKTGMCVCVPCTTHSKGYPFEVPISAEKDSVALSDQVKSI
AWKVRGAIKKGVVSASELQQIRGKIKVIIGL

Download         Length: 336 bp

>T60222 NZ_CP014129:c1958024-1957689 [Pantoea vagans]
ATGGTAAGCCGTTTTGTGCCTGAAGCCGGAGATATCATCTGGGTGGATTTTGATCCGACCAAAGGAAGTGAGCAGGCAGG
TCACAGGCCAGCTGTTGTTCTTAGCCCGTTTGCTTACAACAATAAAACCGGCATGTGTGTCTGTGTACCCTGCACAACGC
ATTCAAAGGGATATCCGTTCGAAGTTCCCATAAGCGCTGAGAAAGATAGCGTTGCCCTATCCGACCAGGTAAAAAGCATC
GCCTGGAAAGTCAGGGGGGCCATCAAAAAAGGTGTCGTTTCCGCAAGCGAACTTCAGCAAATTCGTGGAAAGATAAAAGT
CATCATCGGTTTATAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9213.58 Da        Isoelectric Point: 4.2459

>AT60222 WP_033782896.1 NZ_CP014129:c1958273-1958025 [Pantoea vagans]
MIHGNVKRWGNSPAIRIPATLMQALNLNIDDEIKIDLVEGKLIIEPVKQEVGYSLAELLEGVTEENLHDPVEWGEPVGKE
IW

Download         Length: 249 bp

>AT60222 NZ_CP014129:c1958273-1958025 [Pantoea vagans]
ATGATTCATGGAAATGTTAAACGCTGGGGTAACTCTCCAGCAATACGTATCCCGGCGACATTGATGCAGGCACTCAATCT
TAATATTGATGACGAAATAAAAATCGATTTGGTTGAAGGAAAACTCATTATTGAACCTGTAAAGCAGGAAGTTGGTTACT
CTCTTGCAGAACTGCTTGAAGGCGTGACAGAAGAAAATCTGCACGATCCGGTTGAATGGGGTGAGCCTGTCGGGAAGGAG
ATTTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References