Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1465948..1466182 | Replicon | chromosome |
| Accession | NZ_CP014099 | ||
| Organism | Shigella sonnei strain FDAARGOS_90 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1465949..1466052 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1465948..1466182 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AL477_RS08245 | 1462382..1462642 | + | 261 | WP_077447296.1 | excisionase | - |
| AL477_RS08250 | 1462671..1463125 | + | 455 | Protein_1478 | IS1-like element IS1A family transposase | - |
| AL477_RS08255 | 1463220..1464448 | + | 1229 | WP_088895425.1 | IS3-like element IS2 family transposase | - |
| AL477_RS08260 | 1464459..1464704 | + | 246 | Protein_1480 | IS1 family transposase | - |
| AL477_RS08265 | 1464741..1465817 | + | 1077 | WP_001189101.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 1465948..1466182 | + | 235 | - | - | Antitoxin |
| - | 1465949..1466052 | - | 104 | - | - | Toxin |
| AL477_RS08270 | 1466210..1466551 | - | 342 | WP_000976476.1 | YebY family protein | - |
| AL477_RS08275 | 1466564..1467436 | - | 873 | WP_000879296.1 | copper homeostasis membrane protein CopD | - |
| AL477_RS08280 | 1467440..1467814 | - | 375 | WP_000168735.1 | CopC domain-containing protein YobA | - |
| AL477_RS08285 | 1467953..1468183 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| AL477_RS08290 | 1468286..1468942 | + | 657 | WP_000011652.1 | carbon-nitrogen hydrolase family protein YobB | - |
| AL477_RS08295 | 1468966..1469628 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 | 1438987..1479160 | 40173 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T60127 NZ_CP014099:c1466052-1465949 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT60127 NZ_CP014099:1465948-1466182 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
