Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-GNAT
Location 3609751..3610570 Replicon chromosome
Accession NZ_CP014070
Organism Citrobacter amalonaticus strain FDAARGOS_165

Toxin (Protein)


Gene name yjhX Uniprot ID A0A3S5G4N2
Locus tag AL524_RS43460 Protein ID WP_043001077.1
Coordinates 3610313..3610570 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag AL524_RS43455 Protein ID WP_044328649.1
Coordinates 3609751..3610302 (-) Length 184 a.a.

Genomic Context

AL524_RS43440AL524_RS43485AL524_RS43490AL524_RS43445AL524_RS43450AL524_RS43455AL524_RS43460AL524_RS43470AL524_RS43475AL524_RS43480
Location: 3606260..3607384 (1125 bp)
Type: Others
Protein ID: WP_043001073.1
Location: 3613066..3613854 (789 bp)
Type: Others
Protein ID: WP_043001081.1
Location: 3613859..3614764 (906 bp)
Type: Others
Protein ID: WP_043001082.1
Location: 3607692..3608276 (585 bp)
Type: Others
Protein ID: WP_044264020.1
Location: 3608953..3609699 (747 bp)
Type: Others
Protein ID: WP_061070267.1
Location: 3609751..3610302 (552 bp)
Type: Antitoxin
Protein ID: WP_044328649.1
Location: 3610313..3610570 (258 bp)
Type: Toxin
Protein ID: WP_043001077.1
Location: 3610951..3611147 (197 bp)
Type: Others
Protein ID: Protein_3369
Location: 3611166..3611558 (393 bp)
Type: Others
Protein ID: WP_044328647.1
Location: 3612039..3612830 (792 bp)
Type: Others
Protein ID: WP_061070268.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AL524_RS434403606260..3607384+1125WP_043001073.1hypothetical protein-
AL524_RS434453607692..3608276-585WP_044264020.1hypothetical protein-
AL524_RS434503608953..3609699-747WP_061070267.1class I SAM-dependent methyltransferase-
AL524_RS434553609751..3610302-552WP_044328649.1N-acetyltransferaseAntitoxin
AL524_RS434603610313..3610570-258WP_043001077.1YjhX family toxinToxin
AL524_RS434703610951..3611147-197Protein_3369tryptophan synthase subunit alpha-
AL524_RS434753611166..3611558-393WP_044328647.1VOC family protein-
AL524_RS434803612039..3612830-792WP_061070268.1PhzF family phenazine biosynthesis protein-
AL524_RS434853613066..3613854+789WP_043001081.1IclR family transcriptional regulator-
AL524_RS434903613859..3614764+906WP_043001082.1dihydrodipicolinate synthase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(18-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9490.00 Da        Isoelectric Point: 11.1381

>T60100 WP_043001077.1 NZ_CP014070:c3610570-3610313 [Citrobacter amalonaticus]
MNLSRQEQRTLHVLAKGGRIAHVRDASGRVTAVECYSREGLLLADCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QPDNR

Download         Length: 258 bp

>T60100 NZ_CP014070:c3610570-3610313 [Citrobacter amalonaticus]
ATGAATTTATCCCGTCAGGAACAACGTACCTTACACGTTCTCGCCAAAGGTGGACGTATTGCGCACGTCCGCGATGCGTC
AGGCCGCGTCACCGCCGTTGAATGCTACAGTCGCGAAGGGCTGCTGCTCGCCGACTGTACACTTGCCGTCTTCAAAAAAC
TCAAAACCAAAAAGCTGATCAAATCCGTCAATGGTCAGCCGTACCGCATTAATACCACCGGGCTGAACAACGTGCGTGCT
CAGCCAGATAACCGCTAA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20335.22 Da        Isoelectric Point: 6.0668

>AT60100 WP_044328649.1 NZ_CP014070:c3610302-3609751 [Citrobacter amalonaticus]
MTTRNFTIHITDESDTNDIREVETRAFGYSKEACLVASLLEDDTARPALSLLARQEGNAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGRGVGGLLIRTGIEHLRSMGCQCVFVLGHATYYPRHGFEPCAGDKGFPAPYPIAEEHKACWMMQSLSA
QPFDRAGDIQCAQALMKPEHWRE

Download         Length: 552 bp

>AT60100 NZ_CP014070:c3610302-3609751 [Citrobacter amalonaticus]
ATGACAACACGCAACTTCACTATTCATATTACCGATGAAAGTGATACCAACGACATCCGGGAAGTCGAAACCCGCGCCTT
TGGCTACAGTAAAGAGGCCTGCCTGGTGGCTTCTTTGCTCGAGGACGACACTGCGCGTCCAGCGTTATCGTTACTGGCCA
GACAGGAAGGTAACGCTGTCGGGCATATCCTGTTTACCCGGGCGACATTCAAAGGAGAAATGGATTCCCCTCTGATGCAT
ATCCTTGCTCCCCTGGCGGTCATCCCTGAATACCAGGGGAGGGGCGTGGGCGGATTATTGATTCGTACCGGTATAGAACA
CTTACGTTCGATGGGATGCCAGTGCGTTTTTGTTCTCGGTCATGCCACTTACTATCCGCGACATGGATTTGAACCCTGTG
CAGGAGACAAAGGCTTTCCCGCGCCTTACCCCATTGCGGAGGAACATAAGGCCTGCTGGATGATGCAGTCCCTCTCCGCA
CAACCCTTTGATCGTGCCGGCGACATCCAATGTGCGCAGGCCTTAATGAAACCGGAGCACTGGCGTGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A3S5G4N2

Antitoxin

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Source
ID
Structure
No matching records found

References