Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2489900..2490486 Replicon chromosome
Accession NZ_CP014062
Organism Pseudomonas monteilii strain FDAARGOS_171

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag AL532_RS11920 Protein ID WP_082426425.1
Coordinates 2489900..2490193 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A923H277
Locus tag AL532_RS11925 Protein ID WP_060499950.1
Coordinates 2490190..2490486 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL532_RS11895 2485549..2486403 + 855 WP_060499955.1 putative selenate ABC transporter substrate-binding protein -
AL532_RS11900 2486400..2487209 + 810 WP_104833972.1 ATP-binding cassette domain-containing protein -
AL532_RS11905 2487203..2488030 + 828 WP_104833973.1 ABC transporter permease -
AL532_RS11910 2488027..2488794 + 768 WP_060499952.1 phosphonate ABC transporter, permease protein PhnE -
AL532_RS11915 2488791..2489678 - 888 WP_104833974.1 effector protein -
AL532_RS11920 2489900..2490193 + 294 WP_082426425.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AL532_RS11925 2490190..2490486 + 297 WP_060499950.1 putative addiction module antidote protein Antitoxin
AL532_RS11930 2490488..2490976 - 489 WP_104833975.1 GNAT family N-acetyltransferase -
AL532_RS11935 2491128..2491775 - 648 WP_060499948.1 hypothetical protein -
AL532_RS11940 2492071..2492577 + 507 WP_060499947.1 sigma-70 family RNA polymerase sigma factor -
AL532_RS11945 2492577..2493518 + 942 WP_104833976.1 FecR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2488791..2531781 42990


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10847.80 Da        Isoelectric Point: 10.5184

>T60059 WP_082426425.1 NZ_CP014062:2489900-2490193 [Pseudomonas monteilii]
MYLVEQTESFAVWLSSLRDLKAKLAIGRRLERVAIGNLGDFKWLGGGLGELRIDVGAGYRVYFTQKGHRLVLLLVGGDKS
TQVADILKSRKLLKEMI

Download         Length: 294 bp

>T60059 NZ_CP014062:2489900-2490193 [Pseudomonas monteilii]
ATGTATCTTGTTGAACAGACGGAGAGCTTTGCAGTTTGGCTATCCAGTTTGAGGGATTTGAAAGCCAAGCTTGCGATAGG
TCGCAGGCTGGAGCGAGTTGCGATAGGCAACCTTGGTGACTTCAAGTGGCTTGGAGGCGGTCTAGGTGAGCTTCGCATCG
ACGTAGGTGCAGGCTATCGCGTCTATTTCACGCAAAAGGGGCACAGATTGGTTCTGCTGCTGGTTGGCGGCGACAAGTCC
ACTCAAGTCGCCGATATTCTCAAATCAAGAAAGCTGCTGAAGGAGATGATATGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10587.22 Da        Isoelectric Point: 6.2205

>AT60059 WP_060499950.1 NZ_CP014062:2490190-2490486 [Pseudomonas monteilii]
MSEKLIPFDMAALLSSDEAISEYLSQVLSDGDTEEIIRALGHIARARGMTHIATESGLGRESLYKALSPGAKPRFDTVLK
VIRALGVDLLVQPHAVAR

Download         Length: 297 bp

>AT60059 NZ_CP014062:2490190-2490486 [Pseudomonas monteilii]
ATGAGCGAAAAACTGATTCCGTTTGATATGGCAGCTTTGTTGAGTAGCGATGAGGCCATCAGTGAGTACCTTAGCCAGGT
GCTATCAGATGGCGATACCGAAGAGATCATTCGAGCGCTCGGCCATATCGCGCGTGCACGAGGCATGACACACATAGCCA
CGGAGAGTGGTTTGGGCAGAGAAAGCCTCTACAAGGCGCTCAGCCCAGGCGCAAAGCCTCGTTTTGACACTGTGTTGAAG
GTCATTCGAGCCTTGGGGGTAGACCTTCTCGTGCAGCCCCATGCGGTAGCCCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References