Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 1228409..1229015 Replicon chromosome
Accession NZ_CP014062
Organism Pseudomonas monteilii strain FDAARGOS_171

Toxin (Protein)


Gene name PfiT Uniprot ID -
Locus tag AL532_RS06220 Protein ID WP_104833619.1
Coordinates 1228668..1229015 (+) Length 116 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID A0A923H1P8
Locus tag AL532_RS06215 Protein ID WP_025754068.1
Coordinates 1228409..1228657 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL532_RS28170 1223950..1224108 - 159 WP_192576908.1 hypothetical protein -
AL532_RS06200 1224426..1224740 - 315 WP_192576909.1 helix-turn-helix domain-containing protein -
AL532_RS28175 1224737..1224904 - 168 WP_156351075.1 hypothetical protein -
AL532_RS06205 1224908..1225126 - 219 WP_104833617.1 helix-turn-helix domain-containing protein -
AL532_RS06210 1226164..1227594 - 1431 WP_192576910.1 site-specific integrase -
AL532_RS06215 1228409..1228657 + 249 WP_025754068.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
AL532_RS06220 1228668..1229015 + 348 WP_104833619.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AL532_RS06225 1229053..1231350 - 2298 WP_104833620.1 TonB-dependent siderophore receptor -
AL532_RS06230 1231491..1232213 + 723 WP_060501217.1 response regulator -
AL532_RS06235 1232215..1233582 + 1368 WP_104835399.1 HAMP domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-100)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12781.65 Da        Isoelectric Point: 6.6372

>T60058 WP_104833619.1 NZ_CP014062:1228668-1229015 [Pseudomonas monteilii]
MSKPTIRFTHSASQSIEDQVHHLAVYHGTAAALEKITTLVDTIEHRLAAAPVGYPVSPQASGLGVMQYRELNVDGYRVFY
EVIETDNAIAVGLVLRQKQSVEQTLIRYCLIYPLP

Download         Length: 348 bp

>T60058 NZ_CP014062:1228668-1229015 [Pseudomonas monteilii]
ATGAGTAAGCCGACCATACGCTTCACCCATTCCGCCTCTCAGAGCATCGAAGATCAAGTCCACCATCTGGCCGTCTATCA
CGGTACCGCAGCGGCACTTGAGAAAATCACCACACTGGTCGACACCATTGAGCACCGGCTGGCTGCCGCGCCCGTGGGTT
ACCCGGTCAGCCCACAAGCGAGCGGGCTGGGTGTCATGCAGTATCGTGAGCTGAATGTCGACGGGTACAGGGTGTTCTAC
GAAGTGATCGAAACCGACAATGCCATTGCCGTGGGGTTGGTTCTCAGGCAAAAGCAGAGTGTTGAACAGACATTGATTCG
GTATTGCCTGATTTACCCATTACCTTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9307.61 Da        Isoelectric Point: 6.4706

>AT60058 WP_025754068.1 NZ_CP014062:1228409-1228657 [Pseudomonas monteilii]
MRVETISYLKRHAADLDLEEPMVVTQNGVPAYVVESYADRKQRDEAIALVKLLAIGSREYAQGKHSSAEDLKTRLLKKFS
EE

Download         Length: 249 bp

>AT60058 NZ_CP014062:1228409-1228657 [Pseudomonas monteilii]
ATGCGAGTAGAAACGATCAGCTACCTGAAACGCCATGCTGCTGACCTGGACCTGGAAGAACCCATGGTCGTGACACAGAA
CGGTGTGCCTGCCTATGTGGTCGAGTCCTACGCGGATCGCAAGCAACGGGATGAAGCCATAGCCTTGGTGAAACTGCTCG
CCATCGGTTCCCGTGAGTATGCTCAGGGCAAACACAGCTCGGCCGAAGACCTCAAGACTCGCCTTCTCAAGAAATTTTCT
GAGGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References