Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafN(antitoxin) |
| Location | 854492..855057 | Replicon | chromosome |
| Accession | NZ_CP014053 | ||
| Organism | Vibrio alginolyticus strain FDAARGOS_108 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A0H2MSY5 |
| Locus tag | AL539_RS05490 | Protein ID | WP_015296903.1 |
| Coordinates | 854492..854779 (-) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | AL539_RS05495 | Protein ID | WP_025553688.1 |
| Coordinates | 854776..855057 (-) | Length | 94 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AL539_RS05435 | 849836..850384 | - | 549 | WP_128740525.1 | hypothetical protein | - |
| AL539_RS26365 | 850481..850549 | - | 69 | WP_074531725.1 | DUF3265 domain-containing protein | - |
| AL539_RS05440 | 850624..850872 | + | 249 | Protein_796 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| AL539_RS05445 | 850862..851152 | + | 291 | WP_005377002.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| AL539_RS26370 | 851195..851263 | - | 69 | WP_074531725.1 | DUF3265 domain-containing protein | - |
| AL539_RS05450 | 851338..851586 | + | 249 | WP_005377003.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| AL539_RS05455 | 851576..851866 | + | 291 | WP_005377002.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| AL539_RS05460 | 851885..851977 | - | 93 | WP_080256826.1 | DUF3265 domain-containing protein | - |
| AL539_RS05465 | 851992..852390 | - | 399 | WP_025539256.1 | hypothetical protein | - |
| AL539_RS05470 | 852514..852942 | - | 429 | WP_104975432.1 | GNAT family N-acetyltransferase | - |
| AL539_RS05475 | 853099..853656 | - | 558 | WP_054730719.1 | hypothetical protein | - |
| AL539_RS05480 | 853684..853776 | - | 93 | WP_005433818.1 | DUF3265 domain-containing protein | - |
| AL539_RS05485 | 853791..854330 | - | 540 | WP_104975434.1 | hypothetical protein | - |
| AL539_RS26375 | 854372..854464 | - | 93 | WP_079767280.1 | DUF3265 domain-containing protein | - |
| AL539_RS05490 | 854492..854779 | - | 288 | WP_015296903.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| AL539_RS05495 | 854776..855057 | - | 282 | WP_025553688.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| AL539_RS05500 | 855148..855237 | - | 90 | WP_077680412.1 | DUF3265 domain-containing protein | - |
| AL539_RS05510 | 855758..855850 | - | 93 | WP_128740527.1 | DUF3265 domain-containing protein | - |
| AL539_RS05515 | 856934..857563 | - | 630 | WP_104975436.1 | hypothetical protein | - |
| AL539_RS05520 | 857631..857755 | - | 125 | Protein_813 | DUF3265 domain-containing protein | - |
| AL539_RS26380 | 858203..858283 | - | 81 | WP_172563635.1 | DUF3265 domain-containing protein | - |
| AL539_RS05530 | 858650..858739 | - | 90 | Protein_815 | DUF3265 domain-containing protein | - |
| AL539_RS05535 | 858766..859797 | - | 1032 | WP_054576957.1 | (p)ppGpp synthetase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 787032..862540 | 75508 | |
| - | inside | Integron | - | - | 796577..861422 | 64845 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11003.69 Da Isoelectric Point: 5.1098
>T60042 WP_015296903.1 NZ_CP014053:c854779-854492 [Vibrio alginolyticus]
MKVVWSPLALQKLGDAAEFISLDNPPAAEKWVNEVFDKTELLGSMPEMGRFVPEMPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQILSEDDV
MKVVWSPLALQKLGDAAEFISLDNPPAAEKWVNEVFDKTELLGSMPEMGRFVPEMPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQILSEDDV
Download Length: 288 bp
>T60042 NZ_CP014053:c854779-854492 [Vibrio alginolyticus]
ATGAAAGTAGTCTGGTCTCCATTAGCACTTCAGAAACTAGGTGATGCAGCGGAGTTTATTTCTTTGGATAATCCACCTGC
GGCAGAGAAGTGGGTAAACGAAGTTTTTGATAAAACTGAACTCCTTGGAAGTATGCCTGAAATGGGGCGGTTTGTTCCTG
AAATGCCCCATACGAATTATCGTGAAATCATCTTTGGTCACTATCGTATTATCTACAGTTTAAGCCACGAAATTCGCGTA
CTAACAGTTCGTAATTGTCGTCAAATTTTATCGGAAGATGACGTGTAA
ATGAAAGTAGTCTGGTCTCCATTAGCACTTCAGAAACTAGGTGATGCAGCGGAGTTTATTTCTTTGGATAATCCACCTGC
GGCAGAGAAGTGGGTAAACGAAGTTTTTGATAAAACTGAACTCCTTGGAAGTATGCCTGAAATGGGGCGGTTTGTTCCTG
AAATGCCCCATACGAATTATCGTGAAATCATCTTTGGTCACTATCGTATTATCTACAGTTTAAGCCACGAAATTCGCGTA
CTAACAGTTCGTAATTGTCGTCAAATTTTATCGGAAGATGACGTGTAA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10370.85 Da Isoelectric Point: 5.8650
>AT60042 WP_025553688.1 NZ_CP014053:c855057-854776 [Vibrio alginolyticus]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQALGRIKK
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQALGRIKK
Download Length: 282 bp
>AT60042 NZ_CP014053:c855057-854776 [Vibrio alginolyticus]
ATGAGTCGTATTCATTTCGATCAAGATATTCAGCCTTTGTCTGAGTTTCGCGCTGGTGTAGCTTCATACATCAAACAAAT
CAATGAGACTCGTCGTCCATTGGTGATTACGCAACGTGGCAAAGGTGTTGCTGTTGTTCTCGATGTTGCTGAGTATGAAG
CAATGCAAGAGAAAATCGAATTACTGGAAGAAATGCGCACAGCAGAAGCTCAGTTAGCTTCTGGTCTCGGTGTTTCCAAT
GATGATGCGCGTGCTCAAGCACTTGGGCGCATTAAGAAATGA
ATGAGTCGTATTCATTTCGATCAAGATATTCAGCCTTTGTCTGAGTTTCGCGCTGGTGTAGCTTCATACATCAAACAAAT
CAATGAGACTCGTCGTCCATTGGTGATTACGCAACGTGGCAAAGGTGTTGCTGTTGTTCTCGATGTTGCTGAGTATGAAG
CAATGCAAGAGAAAATCGAATTACTGGAAGAAATGCGCACAGCAGAAGCTCAGTTAGCTTCTGGTCTCGGTGTTTCCAAT
GATGATGCGCGTGCTCAAGCACTTGGGCGCATTAAGAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|