60037

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 134854..136201 Replicon plasmid unnamed1
Accession NZ_CP014052
Organism Vibrio alginolyticus strain FDAARGOS_108

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag AL539_RS00750 Protein ID WP_104975158.1
Coordinates 135260..136201 (+) Length 314 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag AL539_RS00745 Protein ID WP_085343578.1
Coordinates 134854..135258 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL539_RS00725 130701..131924 - 1224 WP_089110674.1 Tm-1-like ATP-binding domain-containing protein -
AL539_RS00730 132079..132750 + 672 WP_089110675.1 TetR/AcrR family transcriptional regulator; helix-turn-helix transcriptional regulator -
AL539_RS00735 133227..133640 - 414 WP_011078484.1 DNA polymerase V -
AL539_RS00740 134072..134665 + 594 WP_104975157.1 tyrosine-type recombinase/integrase -
AL539_RS00745 134854..135258 + 405 WP_085343578.1 S-adenosylhomocysteine hydrolase Antitoxin
AL539_RS00750 135260..136201 + 942 WP_104975158.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
AL539_RS00755 136222..137739 + 1518 WP_104975159.1 type I restriction-modification system subunit M -
AL539_RS00760 137729..138916 + 1188 WP_104975160.1 restriction endonuclease subunit S -
AL539_RS00765 138996..139871 + 876 WP_050567208.1 50S ribosome-binding GTPase -
AL539_RS00770 139871..140470 + 600 WP_104975161.1 50S ribosome-binding GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..217123 217123


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-300)

Antitoxin

Protein of unknown function DUF6088

(7-130)


Sequences

Toxin        


Download         Length: 314 a.a.        Molecular weight: 35842.26 Da        Isoelectric Point: 5.2920

>T60037 WP_104975158.1 NZ_CP014052:135260-136201 [Vibrio alginolyticus]
MNTLKQQFLEVSDALELGNPAIIEKDYWVVALLAELTKISPEHHQMVFSGGTALAKSNVKILRMSEDVDIKLIPNQAFDE
LSRAKKKAARKACVNEIEQAITQSERFTVEERSVRDEYRYVEFELKYPQQFSQAPCLRPIIKLELIETIPLLDVESRSIQ
SLVAELYQQPQEVSAFDCVSIHATLVEKIISMLRRTMSVKRNTERSDDVALVRHIYDVHCITKLSMPELNAIVGLFKAVL
AEDIARFGNQHAEFVVNPKQELQLGLKELEENAIFRQRFQDFVTPMVFNTEPHDFDTCFASFKHIATSLIETI

Download         Length: 942 bp

>T60037 NZ_CP014052:135260-136201 [Vibrio alginolyticus]
ATGAACACACTAAAACAACAATTTCTTGAGGTTTCCGATGCGCTTGAGCTTGGAAACCCAGCCATCATTGAAAAAGATTA
CTGGGTCGTTGCCTTACTAGCCGAACTAACGAAAATTTCCCCTGAGCATCATCAAATGGTCTTTTCTGGCGGCACTGCGT
TGGCGAAATCAAACGTTAAAATTCTAAGAATGTCGGAAGATGTAGATATAAAACTCATCCCCAACCAAGCATTTGATGAA
CTGAGTCGTGCGAAAAAGAAAGCCGCGAGAAAGGCATGTGTTAACGAGATTGAACAGGCGATCACCCAGTCAGAGCGATT
TACCGTTGAAGAGCGTTCTGTGCGAGATGAGTACCGCTACGTCGAGTTTGAACTTAAATACCCGCAGCAGTTTAGTCAAG
CGCCCTGCCTGCGCCCCATCATCAAGTTAGAGTTAATCGAAACCATTCCATTACTGGATGTAGAGTCGCGCAGCATTCAA
TCTCTGGTCGCAGAGTTGTACCAACAACCACAAGAAGTGAGTGCATTTGATTGCGTCTCTATCCATGCCACATTGGTTGA
AAAAATCATTTCGATGCTGCGCCGTACCATGTCGGTAAAACGCAATACGGAGCGAAGTGATGATGTTGCTTTAGTTCGCC
ACATTTACGATGTTCACTGCATAACAAAGCTCTCAATGCCAGAACTCAACGCGATTGTCGGCCTATTCAAAGCGGTATTG
GCAGAAGATATTGCCCGCTTTGGCAATCAACATGCCGAGTTTGTTGTCAACCCCAAACAAGAGCTACAACTTGGCCTCAA
AGAGCTTGAGGAGAATGCAATATTCCGCCAACGCTTTCAGGACTTTGTCACGCCAATGGTGTTTAACACCGAACCCCATG
ATTTTGATACCTGCTTTGCCTCATTTAAACACATTGCAACATCGTTAATTGAAACCATTTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15186.50 Da        Isoelectric Point: 10.5319

>AT60037 WP_085343578.1 NZ_CP014052:134854-135258 [Vibrio alginolyticus]
MTAADRIYQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVQQGELMKLGYGLYTKARINSLTGKPMPTNPGGTDALMRE
ILKMKGVDFEMDSLSLQSLSGSSTQIPSSIQYSWDPKQFNRKLVVGSRVLNLPS

Download         Length: 405 bp

>AT60037 NZ_CP014052:134854-135258 [Vibrio alginolyticus]
ATGACAGCAGCAGACCGCATTTATCAAAAGATAAAGCGTTCAAGACGTTATGTATTTGAACGCAAAGACTTTGATGGATT
TGCAAGTTACGACCAAATAGGTCGGGCCCTGAGGCAGCTTGTACAGCAAGGTGAGTTAATGAAGCTTGGCTATGGCTTGT
ATACCAAAGCAAGAATCAATAGCCTAACAGGCAAGCCTATGCCCACCAATCCAGGTGGGACCGATGCCCTTATGCGAGAA
ATTCTTAAAATGAAAGGCGTTGATTTTGAGATGGATAGTCTATCGCTACAAAGTCTTTCAGGTTCAAGCACCCAAATTCC
ATCTTCTATTCAGTATTCATGGGACCCAAAACAGTTTAATCGCAAACTGGTGGTCGGTAGCCGTGTGCTGAACTTACCAA
GTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References