Detailed information of TA system TA060034

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 29047..29672
• Replicon: plasmid unnamed
• Accession: NZ_CP014050
• Organism: Salmonella enterica strain FDAARGOS_94

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: AL463_RS00185
• Protein ID: WP_000911322.1
• Coordinates: 29047..29445 (-)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: AL463_RS00190
• Protein ID: WP_000450265.1
• Coordinates: 29445..29672 (-)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AL463_RS00170	25157..25651	+	495	WP_010999946.1	entry exclusion protein	-
AL463_RS00175	25687..26418	+	732	WP_000782438.1	complement resistance protein TraT	-
AL463_RS00180	26795..29038	+	2244	WP_000009320.1	type IV conjugative transfer system coupling protein TraD	-
AL463_RS00185	29047..29445	-	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
AL463_RS00190	29445..29672	-	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..93933	93933

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (10-82)

Antitoxin

• Antitoxin MqsA/HigA-2 (1-131)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 19592.50 Da
• Isoelectric Point: 5.5500

>T60034 WP_000911322.1 NZ_CP014050:c29445-29047 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 399 bp

>T60034 NZ_CP014050:c29445-29047 [Salmonella enterica]
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Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 11203.44 Da
• Isoelectric Point: 5.5500

>AT60034 WP_000450265.1 NZ_CP014050:c29672-29445 [Salmonella enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 228 bp

>AT60034 NZ_CP014050:c29672-29445 [Salmonella enterica]
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