59979

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 253567..254227 Replicon chromosome
Accession NZ_CP014031
Organism Hafnia paralvei strain FDAARGOS_158

Toxin (Protein)


Gene name cptA Uniprot ID A0A2A2MBB6
Locus tag AL518_RS01170 Protein ID WP_008815043.1
Coordinates 253567..253980 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A2A2MBZ0
Locus tag AL518_RS01175 Protein ID WP_008815042.1
Coordinates 253961..254227 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL518_RS01150 249412..251145 - 1734 WP_008815047.1 single-stranded-DNA-specific exonuclease RecJ -
AL518_RS01155 251151..251867 - 717 WP_061059193.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
AL518_RS01160 251896..252795 - 900 WP_061059194.1 site-specific tyrosine recombinase XerD -
AL518_RS01165 253000..253518 + 519 WP_061059195.1 flavodoxin FldB -
AL518_RS01170 253567..253980 - 414 WP_008815043.1 protein YgfX Toxin
AL518_RS01175 253961..254227 - 267 WP_008815042.1 FAD assembly factor SdhE Antitoxin
AL518_RS01180 254602..255588 + 987 WP_061059196.1 tRNA-modifying protein YgfZ -
AL518_RS01195 256330..257154 - 825 WP_061059197.1 shikimate 5-dehydrogenase -
AL518_RS01200 257358..258242 - 885 WP_004846922.1 nucleoside-specific channel-forming protein Tsx -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16260.00 Da        Isoelectric Point: 9.1742

>T59979 WP_008815043.1 NZ_CP014031:c253980-253567 [Hafnia paralvei]
VDQWRCDVRVSWRTQLLLLVTHGTLVLLILLAPWPENYSIYWLILLTLVVFESIRSQKQIAKVQGELNFLAENRISWQHQ
EWELCKTPWISDFGALLPLKSLKDQDKRKRLWIAADSLTPEAWSHLRRSLMQMRHDA

Download         Length: 414 bp

>T59979 NZ_CP014031:c253980-253567 [Hafnia paralvei]
GTGGACCAATGGCGTTGTGATGTGAGGGTGTCATGGCGTACACAACTATTACTGTTGGTGACGCATGGCACTCTGGTTTT
ATTGATTTTGTTAGCTCCTTGGCCGGAAAACTACAGTATTTATTGGCTCATTTTGCTGACATTAGTGGTGTTTGAAAGTA
TTCGCAGCCAGAAGCAGATTGCTAAGGTTCAGGGAGAGTTGAATTTTCTGGCGGAAAATCGCATTAGCTGGCAGCACCAA
GAATGGGAGCTATGTAAGACGCCGTGGATCAGTGATTTTGGCGCTTTGCTACCGTTGAAGAGTTTGAAGGATCAGGATAA
AAGAAAGCGTTTGTGGATTGCAGCAGATAGCCTGACGCCAGAAGCGTGGTCTCATTTGCGACGCAGTTTAATGCAGATGC
GTCATGATGCTTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10447.94 Da        Isoelectric Point: 5.5601

>AT59979 WP_008815042.1 NZ_CP014031:c254227-253961 [Hafnia paralvei]
MDIENKSRIHWACRRGMRELDISIMPFFEHEYDSLSDTDKQTFVRLLECDDPDLFNWLMNHGSPKDPELAHMVKLIQTRN
KDRGPMAL

Download         Length: 267 bp

>AT59979 NZ_CP014031:c254227-253961 [Hafnia paralvei]
ATGGATATAGAAAATAAATCACGAATTCATTGGGCGTGTCGCCGTGGGATGCGTGAACTGGATATCTCTATTATGCCGTT
TTTCGAACATGAGTATGATTCACTGAGTGACACAGACAAGCAGACATTTGTACGCTTACTTGAGTGCGACGATCCCGATC
TTTTTAATTGGCTAATGAATCACGGCTCACCAAAAGATCCTGAATTGGCGCATATGGTTAAACTCATTCAAACGCGAAAC
AAAGACCGTGGACCAATGGCGTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2A2MBB6

Antitoxin

Source ID Structure
AlphaFold DB A0A2A2MBZ0

References