Detailed information of TA system TA059931

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 89332..89985
• Replicon: chromosome
• Accession: NZ_CP014019
• Organism: Acinetobacter nosocomialis strain FDAARGOS_129

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: AL533_RS00485
• Protein ID: WP_083008247.1
• Coordinates: 89596..89985 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: N8SCE2
• Locus tag: AL533_RS00480
• Protein ID: WP_002049719.1
• Coordinates: 89332..89589 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AL533_RS00460	84846..85853	+	1008	WP_002049752.1	DNA-directed RNA polymerase subunit alpha	-
AL533_RS00465	85872..86249	+	378	WP_002049717.1	50S ribosomal protein L17	-
AL533_RS00470	86431..87921	+	1491	WP_016804181.1	NAD(P)/FAD-dependent oxidoreductase	-
AL533_RS00475	87970..89142	-	1173	WP_002049748.1	acyl-CoA dehydrogenase family protein	-
AL533_RS00480	89332..89589	+	258	WP_002049719.1	succinate dehydrogenase assembly factor 2	Antitoxin
AL533_RS00485	89596..89985	+	390	WP_083008247.1	hypothetical protein	Toxin
AL533_RS00490	90753..91838	+	1086	WP_002049690.1	hypothetical protein	-
AL533_RS00495	91922..92488	+	567	WP_016804184.1	rhombosortase	-
AL533_RS00500	92676..94871	+	2196	WP_016804185.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15548.59 Da
• Isoelectric Point: 10.0990

>T59931 WP_083008247.1 NZ_CP014019:89596-89985 [Acinetobacter nosocomialis]
MINHLNFKLKYSRFAIIFQFFIGLSLAVLFYQLLPILWWLVGVSLLFISFIFFLKRPQLAQIAHLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFEGHKTLTSVIWFDQIPLSQWKQLKTLEKFY

Nucleotide

• Length: 390 bp

>T59931 NZ_CP014019:89596-89985 [Acinetobacter nosocomialis]
TTGATCAACCATTTGAATTTCAAACTGAAATATAGCCGTTTTGCGATTATATTTCAGTTTTTTATTGGCTTAAGTTTGGC
AGTTCTATTTTATCAACTCCTACCAATACTATGGTGGTTGGTTGGGGTCAGTTTACTATTCATAAGTTTTATTTTCTTTT
TAAAGCGGCCACAGCTCGCTCAAATTGCTCATTTAGATCAAAAATTATGGTCACTTAGCTTTCATTCAGAACAAACAATT
TCTCGGGTAGAGATTTTAAAAATAATTGATTATCAGATTTTCATAGTGGTCTATTTTGAAGGGCATAAGACATTAACTTC
TGTTATTTGGTTTGATCAAATACCTCTATCTCAGTGGAAACAACTTAAAACCTTAGAAAAATTTTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10278.71 Da
• Isoelectric Point: 4.7620

>AT59931 WP_002049719.1 NZ_CP014019:89332-89589 [Acinetobacter nosocomialis]
MSEEMTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT59931 NZ_CP014019:89332-89589 [Acinetobacter nosocomialis]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAGTTTATCGCGCACGCCGCGGTTTAAAGGAAATTGATGTCTATTT
TGACCCGTATGTGAAAAATTATTATTTAAAGGCAGATCCAGCAGAAAAAGCATTGTTTGCTGAATTAGTAGAGCAGGAAG
ATCCTGATTTACTTGATTGGTTTATGGAAGTATCTGAACCGCCACGTACAGAGTTACGTGATTTTATCCATAAATTAAAG
CATTATGTTCATGGCTGA

Structures

Antitoxin

• AlphaFold DB: A0A0Q1QI86