Detailed information of TA system TA059924

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yfjZ-ypjF/CbtA-CbeA
• Location: 3401065..3401829
• Replicon: chromosome
• Accession: NZ_CP014017
• Organism: Serratia liquefaciens strain FDAARGOS_125

Toxin (Protein)

• Gene name: ypjF
• Uniprot ID: -
• Locus tag: AL485_RS16165
• Protein ID: WP_071888889.1
• Coordinates: 3401065..3401433 (-)
• Length: 123 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: AL485_RS16170
• Protein ID: WP_061068979.1
• Coordinates: 3401488..3401829 (-)
• Length: 114 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AL485_RS16135	3396616..3397026	-	411	WP_020828618.1	GNAT family N-acetyltransferase	-
AL485_RS16140	3397371..3398291	-	921	WP_048759763.1	alpha/beta hydrolase	-
AL485_RS16145	3399155..3399430	-	276	WP_071888888.1	type II toxin-antitoxin system RelE/ParE family toxin	-
AL485_RS16150	3399431..3399703	-	273	WP_172958983.1	ribbon-helix-helix domain-containing protein	-
AL485_RS16155	3399787..3400632	-	846	WP_061068977.1	DUF4942 domain-containing protein	-
AL485_RS16160	3400739..3401068	-	330	Protein_3100	hypothetical protein	-
AL485_RS16165	3401065..3401433	-	369	WP_071888889.1	TA system toxin CbtA family protein	Toxin
AL485_RS16170	3401488..3401829	-	342	WP_061068979.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
AL485_RS16175	3401840..3402319	-	480	WP_061069170.1	DNA repair protein RadC	-
AL485_RS16180	3402356..3402823	-	468	WP_172958984.1	antirestriction protein	-
AL485_RS16185	3402976..3404211	-	1236	WP_061068981.1	O-antigen ligase family protein	-
AL485_RS16190	3404269..3405426	-	1158	WP_061068982.1	putative lipopolysaccharide heptosyltransferase III	-
AL485_RS16195	3406137..3406285	-	149	Protein_3107	DUF945 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3399155..3413522	14367

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-111)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 123 a.a.
• Molecular weight: 13576.62 Da
• Isoelectric Point: 8.9186

>T59924 WP_071888889.1 NZ_CP014017:c3401433-3401065 [Serratia liquefaciens]
MQTVSTCPRRAAQPCPSPLAVWQALLTHLLAQHYGLTLSDTAFSDDAVIREHINAGISLADALNFIVEKFDLVRTDRTGF
SCREQSPFITAIDILRARRACGLMTRRGYRTITQTIQGVKQT

Nucleotide

• Length: 369 bp

>T59924 NZ_CP014017:c3401433-3401065 [Serratia liquefaciens]
ATGCAAACAGTATCAACATGCCCAAGACGGGCGGCGCAGCCCTGCCCGTCGCCCCTTGCCGTCTGGCAGGCCTTACTCAC
ACACCTGCTGGCGCAGCATTACGGCCTGACGCTGAGCGATACCGCGTTCAGCGATGATGCCGTCATCCGGGAACACATCA
ACGCCGGTATCTCGCTGGCTGATGCGCTGAATTTTATCGTAGAAAAGTTTGACCTGGTACGCACCGATCGAACGGGATTT
TCCTGCCGGGAGCAATCCCCTTTTATCACTGCAATTGATATTCTGCGGGCCCGACGGGCCTGTGGCTTGATGACCCGACG
TGGTTACCGAACCATTACGCAGACCATACAGGGAGTGAAACAAACATGA

Antitoxin

Protein

• Length: 114 a.a.
• Molecular weight: 12631.30 Da
• Isoelectric Point: 7.2724

>AT59924 WP_061068979.1 NZ_CP014017:c3401829-3401488 [Serratia liquefaciens]
MSTIDVPTWGLKRNITPQLGARLVQQGNRLHYLADRAGISGAFSEAQTRSLDKAFPQFINHLELMLLSGELNPRYQHGVT
LYRDGLTCEADSLGSYGYIYISIYPTPETPTKN

Nucleotide

• Length: 342 bp

>AT59924 NZ_CP014017:c3401829-3401488 [Serratia liquefaciens]
ATGTCTACAATCGATGTCCCCACCTGGGGCCTGAAACGCAACATCACACCGCAGTTGGGTGCCCGCCTGGTGCAGCAAGG
TAACCGACTCCATTATCTGGCCGACCGCGCCGGCATCAGCGGTGCCTTCAGCGAAGCGCAGACCCGTTCACTGGATAAGG
CCTTCCCGCAGTTTATCAACCATCTGGAACTGATGCTGTTGTCCGGGGAACTCAATCCCCGGTATCAGCACGGCGTCACG
CTGTACCGTGACGGATTGACGTGCGAAGCTGATTCACTCGGGAGCTATGGGTACATCTATATATCTATTTATCCGACACC
CGAAACACCCACGAAAAACTGA