Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2149655..2150241 Replicon chromosome
Accession NZ_CP014017
Organism Serratia liquefaciens strain FDAARGOS_125

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AL485_RS10300 Protein ID WP_048762831.1
Coordinates 2149655..2149945 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AL485_RS10305 Protein ID WP_048762830.1
Coordinates 2149954..2150241 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL485_RS10275 2145061..2145585 - 525 WP_048762834.1 NAD(P)H-dependent oxidoreductase -
AL485_RS10280 2145690..2146598 + 909 WP_020824989.1 LysR family transcriptional regulator -
AL485_RS10285 2146882..2149020 + 2139 WP_048762833.1 anaerobic ribonucleoside-triphosphate reductase -
AL485_RS10295 2149194..2149658 + 465 WP_048762832.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
AL485_RS10300 2149655..2149945 - 291 WP_048762831.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
AL485_RS10305 2149954..2150241 - 288 WP_048762830.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
AL485_RS10310 2150346..2151404 - 1059 WP_048762829.1 permease -
AL485_RS10315 2151666..2152391 + 726 WP_172958979.1 phosphonate metabolism transcriptional regulator PhnF -
AL485_RS10320 2152392..2152835 + 444 WP_046374634.1 phosphonate C-P lyase system protein PhnG -
AL485_RS10325 2152838..2153419 + 582 WP_048762827.1 phosphonate C-P lyase system protein PhnH -
AL485_RS10330 2153419..2154504 + 1086 WP_048762826.1 carbon-phosphorus lyase complex subunit PhnI -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-44)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11329.97 Da        Isoelectric Point: 4.5865

>T59921 WP_048762831.1 NZ_CP014017:c2149945-2149655 [Serratia liquefaciens]
MRVEWDEEALRDRERIFDFLYPFNPQAAEQADAEIDKAVKRLLDYPELGKIWYRQARKLLVSQASLLVLYVVVDDVIKVL
AVAHQREKFPDPDIEN

Download         Length: 291 bp

>T59921 NZ_CP014017:c2149945-2149655 [Serratia liquefaciens]
ATGCGTGTCGAATGGGATGAAGAAGCGCTACGGGACAGGGAACGTATTTTTGATTTTCTCTATCCTTTTAATCCACAGGC
TGCTGAGCAGGCTGATGCTGAGATTGATAAGGCAGTGAAGCGCCTGTTGGATTACCCTGAACTCGGTAAAATTTGGTACA
GACAGGCGCGTAAGTTATTGGTCAGCCAGGCTTCGTTATTAGTTTTATACGTTGTTGTCGACGACGTGATTAAGGTTTTA
GCCGTTGCTCATCAACGAGAGAAATTCCCCGACCCCGACATAGAGAACTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11115.46 Da        Isoelectric Point: 5.7954

>AT59921 WP_048762830.1 NZ_CP014017:c2150241-2149954 [Serratia liquefaciens]
MESRIQFRIEDETKRLAQKAAEAKGITLSEACRRLAEQMADEQRATEQHENWLKEKVDAAFARLHEESAVYLDQQQVDES
MDAFKAKVRAKYDRK

Download         Length: 288 bp

>AT59921 NZ_CP014017:c2150241-2149954 [Serratia liquefaciens]
ATGGAAAGCCGTATCCAGTTTCGCATTGAGGATGAGACTAAACGTTTGGCGCAGAAAGCCGCAGAAGCCAAGGGGATCAC
TTTGAGTGAGGCGTGTCGACGTTTGGCTGAGCAAATGGCGGATGAGCAACGGGCCACTGAGCAACATGAAAATTGGTTGA
AAGAAAAGGTTGATGCCGCTTTTGCCCGTTTGCATGAAGAAAGTGCGGTCTATCTCGACCAGCAACAGGTTGATGAAAGC
ATGGATGCCTTTAAGGCAAAAGTCCGAGCGAAATACGACCGAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References