59920

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 1698111..1698670 Replicon chromosome
Accession NZ_CP014017
Organism Serratia liquefaciens strain FDAARGOS_125

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AL485_RS08220 Protein ID WP_048759741.1
Coordinates 1698377..1698670 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AL485_RS08215 Protein ID WP_048759739.1
Coordinates 1698111..1698389 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL485_RS08190 1693446..1694285 - 840 WP_048759736.1 MurR/RpiR family transcriptional regulator -
AL485_RS08195 1694432..1696018 + 1587 WP_048759737.1 gamma-glutamyltransferase -
AL485_RS08200 1696046..1696237 + 192 WP_046374439.1 oxalurate catabolism protein HpxX -
AL485_RS08205 1696234..1697634 + 1401 WP_048759738.1 AtzE family amidohydrolase -
AL485_RS08210 1697638..1698021 + 384 WP_041415223.1 oxalurate catabolism protein HpxZ -
AL485_RS08215 1698111..1698389 + 279 WP_048759739.1 ribbon-helix-helix protein, CopG family Antitoxin
AL485_RS08220 1698377..1698670 + 294 WP_048759741.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AL485_RS08225 1698680..1699564 - 885 WP_041414248.1 siderophore-interacting protein -
AL485_RS08230 1699570..1700793 - 1224 WP_048759743.1 MFS transporter -
AL485_RS08235 1700931..1702676 + 1746 WP_048759744.1 aerobactin synthase IucA -
AL485_RS08240 1702673..1703623 + 951 WP_048759745.1 acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-42)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10768.26 Da        Isoelectric Point: 6.4767

>T59920 WP_048759741.1 NZ_CP014017:1698377-1698670 [Serratia liquefaciens]
VPQLIWTPAALLDIQRLYQFLAAKDRQAAQKAVASIRSSVNILAHHPQAGRPIEDMAIEFREWPIDFGNSGYIIALYHFD
GSTAVLLAVRHQSEAGD

Download         Length: 294 bp

>T59920 NZ_CP014017:1698377-1698670 [Serratia liquefaciens]
GTGCCACAACTGATATGGACGCCTGCCGCACTGCTCGATATTCAGCGACTGTACCAATTTCTGGCAGCCAAAGATCGCCA
GGCTGCGCAAAAGGCCGTGGCATCCATTCGTAGCAGCGTCAATATCCTGGCCCATCATCCTCAGGCCGGTCGACCCATTG
AAGATATGGCAATTGAATTTAGGGAATGGCCGATCGATTTCGGCAACAGCGGCTATATTATTGCCCTGTATCATTTTGAT
GGCAGCACCGCTGTACTGCTGGCAGTGCGCCATCAAAGTGAAGCCGGTGACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10879.06 Da        Isoelectric Point: 5.2146

>AT59920 WP_048759739.1 NZ_CP014017:1698111-1698389 [Serratia liquefaciens]
MTTAASIKIDDELKQRVQQIAATRQRSAHWTMREAIREYVEREEKREALRKDALQAWEMYQTNGKHLTQDEADHWLANLE
KGDDTEIPECHN

Download         Length: 279 bp

>AT59920 NZ_CP014017:1698111-1698389 [Serratia liquefaciens]
ATGACTACCGCTGCATCGATAAAAATTGATGATGAGCTCAAGCAACGGGTGCAACAAATCGCGGCCACGCGTCAGCGAAG
TGCGCACTGGACTATGCGCGAGGCTATCCGTGAATACGTCGAGCGAGAAGAAAAGCGCGAAGCGCTGCGCAAAGACGCAC
TGCAAGCCTGGGAAATGTATCAGACCAATGGTAAACATCTGACCCAAGACGAGGCTGACCATTGGCTCGCTAATCTGGAA
AAAGGTGATGATACGGAGATACCGGAGTGCCACAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References