Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1415002..1415537 Replicon chromosome
Accession NZ_CP014015
Organism Citrobacter amalonaticus strain FDAARGOS_122

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AL479_RS06795 Protein ID WP_061075550.1
Coordinates 1415250..1415537 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AL479_RS06790 Protein ID WP_061075549.1
Coordinates 1415002..1415253 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL479_RS06760 1410419..1411177 + 759 WP_061075543.1 phosphonate C-P lyase system protein PhnK -
AL479_RS06765 1411299..1411985 + 687 WP_061075544.1 phosphonate C-P lyase system protein PhnL -
AL479_RS06770 1411982..1413118 + 1137 WP_061075545.1 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
AL479_RS06775 1413121..1413675 + 555 WP_061075546.1 ribose 1,5-bisphosphokinase -
AL479_RS06780 1413662..1414096 + 435 WP_061075547.1 aminoalkylphosphonate N-acetyltransferase -
AL479_RS06785 1414161..1414919 + 759 WP_061075548.1 phosphonate metabolism protein PhnP -
AL479_RS06790 1415002..1415253 + 252 WP_061075549.1 antitoxin Antitoxin
AL479_RS06795 1415250..1415537 + 288 WP_061075550.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AL479_RS06800 1415534..1415869 - 336 WP_061075551.1 hypothetical protein -
AL479_RS06805 1416160..1418307 + 2148 WP_081093644.1 formate dehydrogenase subunit alpha -
AL479_RS06810 1418411..1419100 + 690 WP_061075553.1 sel1 repeat family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11045.03 Da        Isoelectric Point: 10.4714

>T59893 WP_061075550.1 NZ_CP014015:1415250-1415537 [Citrobacter amalonaticus]
MSYTVKFREDALKEWQKLGKTIQQQFAKKLKKCCDNPHVPSAKLRGIKDCYKIKLRTSGFRLVYQVIDDVLVIAVVAVGK
RERSEVYQLASDRLR

Download         Length: 288 bp

>T59893 NZ_CP014015:1415250-1415537 [Citrobacter amalonaticus]
ATGAGTTATACGGTAAAGTTCAGGGAAGACGCGCTGAAAGAATGGCAAAAACTTGGTAAAACCATTCAGCAGCAATTTGC
TAAAAAACTGAAGAAATGCTGTGACAATCCCCATGTCCCCTCAGCAAAGCTGAGAGGAATCAAAGATTGCTACAAAATCA
AATTGAGAACCTCAGGCTTTCGCCTTGTTTATCAAGTGATTGATGACGTATTGGTTATCGCCGTCGTTGCTGTCGGTAAA
CGTGAGCGTAGTGAGGTTTATCAACTCGCCAGCGACAGACTGCGTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9177.49 Da        Isoelectric Point: 4.2493

>AT59893 WP_061075549.1 NZ_CP014015:1415002-1415253 [Citrobacter amalonaticus]
MPHIILSDTTASVSELKKNPMATVNAGDGYPVAILNRNQPAFYCIPAALYEKMLDALDDQQLAKLVNERSQQPLVEVDLD
SYL

Download         Length: 252 bp

>AT59893 NZ_CP014015:1415002-1415253 [Citrobacter amalonaticus]
ATGCCACACATCATCTTGAGCGATACCACGGCCAGCGTGAGTGAGTTAAAAAAGAATCCGATGGCGACTGTCAACGCCGG
TGATGGTTATCCCGTCGCGATTCTGAACCGTAACCAGCCCGCTTTTTATTGTATTCCCGCAGCGCTTTACGAAAAAATGC
TGGATGCTCTGGACGATCAGCAACTGGCAAAATTAGTAAATGAACGTAGCCAACAGCCGCTTGTGGAAGTGGATCTGGAC
AGCTACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References