Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/upstrm_HI1419-dnstrm_HI1420 |
Location | 4127307..4127955 | Replicon | chromosome |
Accession | NZ_CP014014 | ||
Organism | Stenotrophomonas maltophilia strain FDAARGOS_92 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | - |
Locus tag | AL480_RS19395 | Protein ID | WP_033833615.1 |
Coordinates | 4127307..4127594 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | - |
Locus tag | AL480_RS19400 | Protein ID | WP_033833616.1 |
Coordinates | 4127653..4127955 (+) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
AL480_RS19365 | 4123249..4124028 | - | 780 | WP_172958429.1 | zinc-dependent peptidase | - |
AL480_RS19370 | 4123995..4124273 | - | 279 | WP_005407696.1 | hypothetical protein | - |
AL480_RS19375 | 4124418..4125386 | + | 969 | WP_033833474.1 | bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor | - |
AL480_RS19380 | 4125383..4126114 | + | 732 | WP_005407698.1 | type III pantothenate kinase | - |
AL480_RS19385 | 4126124..4126984 | + | 861 | WP_033833475.1 | SPOR domain-containing protein | - |
AL480_RS19395 | 4127307..4127594 | + | 288 | WP_033833615.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
AL480_RS19400 | 4127653..4127955 | + | 303 | WP_033833616.1 | putative addiction module antidote protein | Antitoxin |
AL480_RS19410 | 4128409..4128816 | - | 408 | WP_033833617.1 | hypothetical protein | - |
AL480_RS19415 | 4129409..4130179 | + | 771 | WP_033833618.1 | DUF3011 domain-containing protein | - |
AL480_RS19420 | 4130204..4130550 | - | 347 | Protein_3767 | hypothetical protein | - |
AL480_RS19425 | 4130681..4131601 | + | 921 | WP_033833619.1 | arginase | - |
AL480_RS19430 | 4131762..4131899 | + | 138 | WP_005407710.1 | entericidin A/B family lipoprotein | - |
AL480_RS19435 | 4132107..4132328 | + | 222 | WP_004153772.1 | CsbD family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 10765.37 Da Isoelectric Point: 10.4257
>T59891 WP_033833615.1 NZ_CP014014:4127307-4127594 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARIGRLTEGHPGDHRYLGDGISELRVDAGPGYCLYYTQRGRQLLILLVGGDKSS
QQRDIEKAREIARAL
MKIQRTRQFATWIDALKDVTARARILARIGRLTEGHPGDHRYLGDGISELRVDAGPGYCLYYTQRGRQLLILLVGGDKSS
QQRDIEKAREIARAL
Download Length: 288 bp
>T59891 NZ_CP014014:4127307-4127594 [Stenotrophomonas maltophilia]
ATGAAGATCCAGCGTACCCGTCAGTTCGCGACATGGATTGACGCTCTCAAGGACGTAACTGCGCGCGCTCGCATCCTGGC
CCGCATCGGTCGGCTCACCGAAGGCCATCCGGGCGATCACCGCTATCTGGGGGACGGTATTTCCGAACTGCGTGTCGATG
CAGGGCCGGGCTACTGCCTGTACTACACCCAGCGCGGCAGGCAGTTGCTGATTCTTTTGGTCGGAGGTGACAAAAGCTCA
CAGCAACGCGATATCGAAAAGGCCAGGGAGATTGCACGTGCCCTGTGA
ATGAAGATCCAGCGTACCCGTCAGTTCGCGACATGGATTGACGCTCTCAAGGACGTAACTGCGCGCGCTCGCATCCTGGC
CCGCATCGGTCGGCTCACCGAAGGCCATCCGGGCGATCACCGCTATCTGGGGGACGGTATTTCCGAACTGCGTGTCGATG
CAGGGCCGGGCTACTGCCTGTACTACACCCAGCGCGGCAGGCAGTTGCTGATTCTTTTGGTCGGAGGTGACAAAAGCTCA
CAGCAACGCGATATCGAAAAGGCCAGGGAGATTGCACGTGCCCTGTGA
Antitoxin
Download Length: 101 a.a. Molecular weight: 10736.34 Da Isoelectric Point: 8.0344
>AT59891 WP_033833616.1 NZ_CP014014:4127653-4127955 [Stenotrophomonas maltophilia]
MATKKKVELKAFDVAEHLRTPEEMAAYLDACIEESEGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FATILKVTRALGVRLHASAV
MATKKKVELKAFDVAEHLRTPEEMAAYLDACIEESEGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FATILKVTRALGVRLHASAV
Download Length: 303 bp
>AT59891 NZ_CP014014:4127653-4127955 [Stenotrophomonas maltophilia]
ATGGCCACTAAGAAAAAAGTCGAACTCAAAGCATTTGATGTGGCCGAACACCTTCGGACACCCGAAGAAATGGCCGCCTA
TCTCGACGCCTGCATCGAGGAAAGCGAGGGCGATTCCGCATTCATCGCTAAGGCGCTTGGCGACATCGCGCGCGCTCAGG
GTATGAGCAAGGTTGCGCGCGCGGCGGGCCTGTCGCGCGAGAGCCTTTACCGCGCACTGTCCGGCGAACGCAGCCCCGAT
TTCGCCACCATCCTGAAGGTGACCCGTGCCTTGGGTGTGCGCCTGCATGCCAGTGCCGTGTGA
ATGGCCACTAAGAAAAAAGTCGAACTCAAAGCATTTGATGTGGCCGAACACCTTCGGACACCCGAAGAAATGGCCGCCTA
TCTCGACGCCTGCATCGAGGAAAGCGAGGGCGATTCCGCATTCATCGCTAAGGCGCTTGGCGACATCGCGCGCGCTCAGG
GTATGAGCAAGGTTGCGCGCGCGGCGGGCCTGTCGCGCGAGAGCCTTTACCGCGCACTGTCCGGCGAACGCAGCCCCGAT
TTCGCCACCATCCTGAAGGTGACCCGTGCCTTGGGTGTGCGCCTGCATGCCAGTGCCGTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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