Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4127307..4127955 Replicon chromosome
Accession NZ_CP014014
Organism Stenotrophomonas maltophilia strain FDAARGOS_92

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag AL480_RS19395 Protein ID WP_033833615.1
Coordinates 4127307..4127594 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag AL480_RS19400 Protein ID WP_033833616.1
Coordinates 4127653..4127955 (+) Length 101 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AL480_RS19365 4123249..4124028 - 780 WP_172958429.1 zinc-dependent peptidase -
AL480_RS19370 4123995..4124273 - 279 WP_005407696.1 hypothetical protein -
AL480_RS19375 4124418..4125386 + 969 WP_033833474.1 bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor -
AL480_RS19380 4125383..4126114 + 732 WP_005407698.1 type III pantothenate kinase -
AL480_RS19385 4126124..4126984 + 861 WP_033833475.1 SPOR domain-containing protein -
AL480_RS19395 4127307..4127594 + 288 WP_033833615.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AL480_RS19400 4127653..4127955 + 303 WP_033833616.1 putative addiction module antidote protein Antitoxin
AL480_RS19410 4128409..4128816 - 408 WP_033833617.1 hypothetical protein -
AL480_RS19415 4129409..4130179 + 771 WP_033833618.1 DUF3011 domain-containing protein -
AL480_RS19420 4130204..4130550 - 347 Protein_3767 hypothetical protein -
AL480_RS19425 4130681..4131601 + 921 WP_033833619.1 arginase -
AL480_RS19430 4131762..4131899 + 138 WP_005407710.1 entericidin A/B family lipoprotein -
AL480_RS19435 4132107..4132328 + 222 WP_004153772.1 CsbD family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 96 a.a.        Molecular weight: 10765.37 Da        Isoelectric Point: 10.4257

>T59891 WP_033833615.1 NZ_CP014014:4127307-4127594 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARIGRLTEGHPGDHRYLGDGISELRVDAGPGYCLYYTQRGRQLLILLVGGDKSS
QQRDIEKAREIARAL

Download         Length: 288 bp

>T59891 NZ_CP014014:4127307-4127594 [Stenotrophomonas maltophilia]
ATGAAGATCCAGCGTACCCGTCAGTTCGCGACATGGATTGACGCTCTCAAGGACGTAACTGCGCGCGCTCGCATCCTGGC
CCGCATCGGTCGGCTCACCGAAGGCCATCCGGGCGATCACCGCTATCTGGGGGACGGTATTTCCGAACTGCGTGTCGATG
CAGGGCCGGGCTACTGCCTGTACTACACCCAGCGCGGCAGGCAGTTGCTGATTCTTTTGGTCGGAGGTGACAAAAGCTCA
CAGCAACGCGATATCGAAAAGGCCAGGGAGATTGCACGTGCCCTGTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10736.34 Da        Isoelectric Point: 8.0344

>AT59891 WP_033833616.1 NZ_CP014014:4127653-4127955 [Stenotrophomonas maltophilia]
MATKKKVELKAFDVAEHLRTPEEMAAYLDACIEESEGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FATILKVTRALGVRLHASAV

Download         Length: 303 bp

>AT59891 NZ_CP014014:4127653-4127955 [Stenotrophomonas maltophilia]
ATGGCCACTAAGAAAAAAGTCGAACTCAAAGCATTTGATGTGGCCGAACACCTTCGGACACCCGAAGAAATGGCCGCCTA
TCTCGACGCCTGCATCGAGGAAAGCGAGGGCGATTCCGCATTCATCGCTAAGGCGCTTGGCGACATCGCGCGCGCTCAGG
GTATGAGCAAGGTTGCGCGCGCGGCGGGCCTGTCGCGCGAGAGCCTTTACCGCGCACTGTCCGGCGAACGCAGCCCCGAT
TTCGCCACCATCCTGAAGGTGACCCGTGCCTTGGGTGTGCGCCTGCATGCCAGTGCCGTGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References