Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3356957..3357102 Replicon chromosome
Accession NZ_CP014010
Organism Klebsiella pneumoniae subsp. pneumoniae strain RJF999

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3356964..3357066 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3356957..3357102 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RJF9_RS16465 3352489..3353922 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
RJF9_RS16470 3354038..3354277 + 240 WP_002911393.1 YebV family protein -
RJF9_RS16475 3354375..3354566 + 192 WP_002911395.1 YebW family protein -
RJF9_RS16480 3354563..3355216 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
RJF9_RS16485 3355373..3356341 + 969 WP_014907334.1 VirK/YbjX family protein -
RJF9_RS30975 3356446..3356589 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3356957..3357102 + 146 - - Antitoxin
- 3356964..3357066 - 103 - - Toxin
RJF9_RS16495 3357225..3357563 - 339 WP_002911404.1 YebY family protein -
RJF9_RS16500 3357580..3358449 - 870 WP_014907333.1 copper homeostasis membrane protein CopD -
RJF9_RS16505 3358453..3358827 - 375 WP_004151448.1 CopC domain-containing protein YobA -
RJF9_RS16510 3358940..3359170 + 231 WP_002911406.1 DNA polymerase III subunit theta -
RJF9_RS16515 3359249..3359908 + 660 WP_002911407.1 exodeoxyribonuclease X -
RJF9_RS16520 3359912..3361972 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T59873 NZ_CP014010:c3357066-3356964 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT59873 NZ_CP014010:3356957-3357102 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References