Detailed information of TA system TA059840

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 3847767..3848561
• Replicon: chromosome
• Accession: NZ_CP014007
• Organism: Kosakonia oryzae strain Ola 51

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: AWR26_RS18085
• Protein ID: WP_064567915.1
• Coordinates: 3848040..3848561 (+)
• Length: 174 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: AWR26_RS18080
• Protein ID: WP_007373817.1
• Coordinates: 3847767..3848036 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AWR26_RS18045	3843712..3844326	+	615	WP_064567902.1	methylthioribulose 1-phosphate dehydratase	-
AWR26_RS18050	3844323..3845012	+	690	WP_064567904.1	acireductone synthase	-
AWR26_RS18055	3845009..3845551	+	543	WP_064567906.1	acireductone dioxygenase	-
AWR26_RS18060	3845702..3846211	-	510	WP_064567907.1	hypothetical protein	-
AWR26_RS18065	3846227..3846682	-	456	WP_064567909.1	hypothetical protein	-
AWR26_RS18070	3846825..3847004	-	180	WP_064567911.1	hypothetical protein	-
AWR26_RS18075	3847244..3847561	+	318	WP_064567913.1	hypothetical protein	-
AWR26_RS18080	3847767..3848036	+	270	WP_007373817.1	DUF1778 domain-containing protein	Antitoxin
AWR26_RS18085	3848040..3848561	+	522	WP_064567915.1	GNAT family N-acetyltransferase	Toxin
AWR26_RS18090	3848747..3849319	+	573	WP_064567917.1	DUF1349 domain-containing protein	-
AWR26_RS18095	3849748..3851286	+	1539	WP_064567919.1	MCP four helix bundle domain-containing protein	-
AWR26_RS18100	3851377..3851652	-	276	WP_175518614.1	MafI family immunity protein	-
AWR26_RS18105	3851649..3851978	-	330	WP_064567921.1	SdpI family protein	-
AWR26_RS18110	3852208..3852981	-	774	WP_007373810.1	hypothetical protein	-
AWR26_RS18115	3852984..3853181	-	198	WP_007373809.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (90-150)

Antitoxin

• Vibrio phage ICP1, Orf50 (8-86)

Sequences

Toxin

Protein

• Length: 174 a.a.
• Molecular weight: 19489.41 Da
• Isoelectric Point: 8.9245

>T59840 WP_064567915.1 NZ_CP014007:3848040-3848561 [Kosakonia oryzae]
VDNLTIEMFSGETEYETGGFDCGEVSLNAFLTNHLKRQHDGKILRAWLLVTKTPRPRILGYYTLSGGSFEKEQLPTKTQQ
KKVPYRNVPCVILGRLAIDKSLQGNGWGETLVAHAMRVVYSASLTIGVYGLFVEALTGNAKKFYEKLGFIPLADRNQHSL
FFPTKSIERLFEE

Nucleotide

• Length: 522 bp

>T59840 NZ_CP014007:3848040-3848561 [Kosakonia oryzae]
GTGGACAACCTGACCATCGAGATGTTCTCAGGAGAGACAGAGTATGAAACAGGAGGTTTTGATTGTGGTGAGGTATCGCT
CAACGCTTTTTTAACCAACCATCTCAAACGCCAGCATGATGGCAAAATTTTACGCGCCTGGCTCCTCGTAACGAAAACAC
CCAGGCCGCGCATTTTAGGCTATTACACCTTGTCTGGCGGCAGTTTCGAGAAAGAACAACTGCCTACAAAAACACAGCAA
AAAAAGGTGCCCTATCGCAATGTCCCCTGCGTCATATTAGGTCGGCTCGCTATTGATAAGTCACTCCAGGGAAACGGCTG
GGGAGAAACCCTGGTAGCGCACGCAATGAGGGTGGTTTACAGTGCCTCACTTACCATCGGCGTATATGGATTATTTGTCG
AAGCACTCACTGGCAACGCCAAAAAATTCTATGAAAAGCTGGGCTTCATTCCTTTAGCCGATCGCAATCAGCATTCGCTG
TTCTTTCCAACAAAGTCTATTGAACGCCTGTTCGAAGAGTAA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10273.77 Da
• Isoelectric Point: 7.0179

>AT59840 WP_007373817.1 NZ_CP014007:3847767-3848036 [Kosakonia oryzae]
MPALKKQRIDLRLTDEDKKMIEEAAAMTNQTVTQFLVNSASERAAEVIEQHRRLILSEESWNRVMDAIENPPAPNDKLKR
AAKRLQNME

Nucleotide

• Length: 270 bp

>AT59840 NZ_CP014007:3847767-3848036 [Kosakonia oryzae]
ATGCCCGCACTGAAAAAACAGCGTATAGATCTGCGACTAACGGATGAGGATAAGAAAATGATCGAAGAAGCGGCAGCAAT
GACCAATCAGACGGTCACACAGTTTCTGGTTAACAGCGCTTCTGAACGCGCCGCGGAAGTGATTGAACAGCACCGTCGCC
TGATTCTCAGCGAGGAATCATGGAACAGGGTTATGGATGCTATCGAAAACCCACCAGCACCGAATGACAAACTTAAACGC
GCCGCAAAACGTCTGCAAAACATGGAGTGA