Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 247975..248120 Replicon chromosome
Accession NZ_CP014004
Organism Klebsiella pneumoniae subsp. pneumoniae strain NUHL24835

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 248011..248113 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 247975..248120 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWN66_RS01180 243105..245165 + 2061 WP_004151449.1 oligopeptidase B -
AWN66_RS01185 245169..245828 - 660 WP_004180433.1 exodeoxyribonuclease X -
AWN66_RS01190 245907..246137 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AWN66_RS01195 246250..246624 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AWN66_RS01200 246628..247497 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
AWN66_RS01205 247514..247852 + 339 WP_002911404.1 YebY family protein -
- 247975..248120 - 146 - - Antitoxin
- 248011..248113 + 103 - - Toxin
AWN66_RS29140 248489..248632 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AWN66_RS01215 248737..249705 - 969 WP_004151446.1 VirK/YbjX family protein -
AWN66_RS01220 249862..250515 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
AWN66_RS01225 250512..250703 - 192 WP_002911395.1 YebW family protein -
AWN66_RS01230 250801..251040 - 240 WP_002911393.1 YebV family protein -
AWN66_RS01235 251156..252589 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T59810 NZ_CP014004:248011-248113 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT59810 NZ_CP014004:c248120-247975 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References