Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ypjF-yeeU/CbtA-CbeA
Location 1164104..1164720 Replicon chromosome
Accession NZ_CP013990
Organism Leclercia adecarboxylata strain USDA-ARS-USMARC-60222

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag APT61_RS22500 Protein ID WP_071886425.1
Coordinates 1164104..1164433 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag APT61_RS05490 Protein ID WP_059307363.1
Coordinates 1164472..1164720 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APT61_RS05460 1159164..1160039 + 876 WP_059307358.1 N-acetylmannosamine kinase -
APT61_RS05465 1160036..1160500 + 465 WP_059307359.1 YhcH/YjgK/YiaL family protein -
APT61_RS05470 1160544..1161398 - 855 WP_059309077.1 kinase -
APT61_RS05475 1161469..1162371 - 903 WP_059307360.1 LysR family transcriptional regulator -
APT61_RS05480 1162480..1163481 + 1002 WP_059307361.1 zinc-binding alcohol dehydrogenase family protein -
APT61_RS05485 1163498..1163788 + 291 WP_167347886.1 antibiotic biosynthesis monooxygenase -
APT61_RS22500 1164104..1164433 - 330 WP_071886425.1 TA system toxin CbtA family protein Toxin
APT61_RS05490 1164472..1164720 - 249 WP_059307363.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
APT61_RS05500 1165147..1167456 + 2310 WP_059307365.1 TerB N-terminal domain-containing protein -
APT61_RS05505 1167460..1168776 + 1317 WP_059307366.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-108)

Antitoxin

Antitoxin CbeA

(1-78)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12460.00 Da        Isoelectric Point: 6.6379

>T59777 WP_071886425.1 NZ_CP013990:c1164433-1164104 [Leclercia adecarboxylata]
MQTLSSHPTRATHPCLSPVETWQRLLTHLLSQHYGLTLNDTPSSNETTIREHIDAGVSLSDAVNFLVEKYELVRIDREGF
SWQQQTPYISVVDILRARRSSDLLKTNVQ

Download         Length: 330 bp

>T59777 NZ_CP013990:c1164433-1164104 [Leclercia adecarboxylata]
ATGCAAACCTTATCATCACACCCAACACGGGCGACTCATCCCTGCCTGTCACCCGTTGAAACCTGGCAACGCCTGTTGAC
TCATCTGTTATCACAGCACTATGGCCTGACGCTGAATGACACACCGTCCAGTAATGAAACCACCATACGGGAACATATTG
ATGCTGGAGTATCGCTTAGCGATGCGGTGAACTTTCTGGTAGAAAAATACGAGCTTGTCCGTATCGACCGGGAGGGGTTT
TCGTGGCAACAACAGACCCCGTATATTTCCGTAGTAGATATTCTGCGAGCAAGGCGCTCTAGCGACTTGCTAAAAACTAA
CGTGCAATGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9246.70 Da        Isoelectric Point: 6.1950

>AT59777 WP_059307363.1 NZ_CP013990:c1164720-1164472 [Leclercia adecarboxylata]
MHFLADRAGFNGALTDEDVLRLDQAFLLILKQLELMVISGKLNSRYQHCVTLYHKGLTCKADTLGPCGYIYIAIYPDQSE
PQ

Download         Length: 249 bp

>AT59777 NZ_CP013990:c1164720-1164472 [Leclercia adecarboxylata]
CTGCATTTTCTCGCTGACCGGGCCGGATTCAACGGAGCTTTGACCGACGAGGATGTGTTGCGCCTGGACCAGGCTTTTCT
CCTGATACTCAAGCAACTGGAACTAATGGTCATCAGCGGCAAGCTAAATTCTCGCTATCAGCACTGCGTTACGCTTTACC
ACAAGGGACTCACCTGTAAAGCTGATACACTCGGTCCCTGTGGTTATATCTATATCGCTATTTATCCCGACCAGTCTGAA
CCGCAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References