Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 874620..875280 Replicon chromosome
Accession NZ_CP013990
Organism Leclercia adecarboxylata strain USDA-ARS-USMARC-60222

Toxin (Protein)


Gene name cptA Uniprot ID A0A7H0FEK5
Locus tag APT61_RS04185 Protein ID WP_032613858.1
Coordinates 874867..875280 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A6G7TIV6
Locus tag APT61_RS04180 Protein ID WP_032613860.1
Coordinates 874620..874886 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APT61_RS04155 869739..871172 - 1434 WP_059307240.1 6-phospho-beta-glucosidase -
APT61_RS04160 871285..872016 - 732 WP_032613869.1 MurR/RpiR family transcriptional regulator -
APT61_RS04165 872069..872380 + 312 WP_032613867.1 N(4)-acetylcytidine aminohydrolase -
APT61_RS04170 872546..873205 + 660 WP_059307241.1 hemolysin III family protein -
APT61_RS04175 873335..874315 - 981 WP_032613862.1 tRNA-modifying protein YgfZ -
APT61_RS04180 874620..874886 + 267 WP_032613860.1 FAD assembly factor SdhE Antitoxin
APT61_RS04185 874867..875280 + 414 WP_032613858.1 protein YgfX Toxin
APT61_RS04190 875285..875806 - 522 WP_059307242.1 flavodoxin FldB -
APT61_RS04195 875908..876804 + 897 WP_059307243.1 site-specific tyrosine recombinase XerD -
APT61_RS04200 876830..877543 + 714 WP_032613852.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
APT61_RS04205 877549..879282 + 1734 WP_059307244.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16231.98 Da        Isoelectric Point: 10.6531

>T59776 WP_032613858.1 NZ_CP013990:874867-875280 [Leclercia adecarboxylata]
VVLWQSDLRVSWRAQWMSLLLHGLVAACILLIPWPLSYTPLWLILLSLVVFDSVRSQRRINSRQGEIKLFMDSRLQWQGS
EWEIIGTPWMLNSGMMLRLRKGDGKRYQHLWLSADSMDEGEWRDLRRMLSQQPTHGR

Download         Length: 414 bp

>T59776 NZ_CP013990:874867-875280 [Leclercia adecarboxylata]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCGTGGCGCGCCCAGTGGATGTCTCTTTTGCTCCACGGCCTGGTTGCGGC
TTGCATCCTGTTGATACCATGGCCGCTAAGCTACACCCCGTTATGGTTAATCTTACTGTCGCTGGTGGTGTTTGACAGCG
TACGCAGCCAACGGCGCATCAATTCCCGTCAGGGCGAAATCAAGCTATTCATGGATTCCCGCCTGCAGTGGCAGGGTAGC
GAGTGGGAAATTATCGGTACGCCGTGGATGCTCAATTCCGGCATGATGCTCCGCTTACGCAAGGGCGACGGGAAACGCTA
CCAGCATTTGTGGTTGTCGGCAGACAGCATGGATGAAGGGGAGTGGCGGGATCTGCGCCGGATGCTTTCGCAGCAACCGA
CGCACGGGCGGTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10539.06 Da        Isoelectric Point: 4.6787

>AT59776 WP_032613860.1 NZ_CP013990:874620-874886 [Leclercia adecarboxylata]
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKKLFIRLLENDDPDLFNWLMNHGEPADAELQRMVLLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT59776 NZ_CP013990:874620-874886 [Leclercia adecarboxylata]
ATGGACATTACTAACAAAGCCCGCATTCATTGGGCATGCCGTCGCGGTATGCGCGAACTCGATATCTCCATCATGCCGTT
CTTCGAATACGAATACGACACCCTGAGCGATGAGGATAAAAAGCTGTTTATCCGCCTGCTGGAGAACGACGATCCTGATT
TATTTAACTGGTTAATGAATCACGGCGAACCCGCCGACGCCGAACTGCAACGGATGGTGCTTTTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7H0FEK5

Antitoxin

Source ID Structure
AlphaFold DB A0A6G7TIV6

References