Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1910727..1910871 Replicon chromosome
Accession NZ_CP013985
Organism Klebsiella variicola strain LMG 23571

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1910763..1910865 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1910727..1910871 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWN63_RS09430 1905857..1907917 + 2061 WP_012541258.1 oligopeptidase B -
AWN63_RS09435 1907921..1908580 - 660 WP_012541259.1 exodeoxyribonuclease X -
AWN63_RS09440 1908659..1908889 - 231 WP_012541260.1 DNA polymerase III subunit theta -
AWN63_RS09445 1909003..1909377 + 375 WP_012541261.1 CopC domain-containing protein YobA -
AWN63_RS09450 1909381..1910250 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
AWN63_RS09455 1910267..1910605 + 339 WP_008804271.1 YebY family protein -
- 1910727..1910871 - 145 - - Antitoxin
- 1910763..1910865 + 103 - - Toxin
AWN63_RS28950 1911250..1911393 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
AWN63_RS09465 1911497..1912465 - 969 WP_162493241.1 VirK/YbjX family protein -
AWN63_RS09470 1912622..1913275 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
AWN63_RS09475 1913272..1913463 - 192 WP_002911395.1 YebW family protein -
AWN63_RS09480 1913561..1913800 - 240 WP_002911393.1 YebV family protein -
AWN63_RS09485 1913916..1915349 - 1434 WP_046881617.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T59751 NZ_CP013985:1910763-1910865 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT59751 NZ_CP013985:c1910871-1910727 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References