Detailed information of TA system TA059731

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2064740..2065296
• Replicon: chromosome
• Accession: NZ_CP013961
• Organism: Xanthomonas oryzae pv. oryzae strain PXO145

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: ATY43_RS09500
• Protein ID: WP_027703932.1
• Coordinates: 2064740..2065030 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: ATY43_RS09505
• Protein ID: WP_011408759.1
• Coordinates: 2065018..2065296 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ATY43_RS09465	2060510..2061601	+	1092	WP_011408756.1	ribonuclease D	-
ATY43_RS09470	2061698..2062014	-	317	Protein_1780	ATP-dependent DNA ligase	-
ATY43_RS27215	2062074..2062280	-	207	Protein_1781	hypothetical protein	-
ATY43_RS24935	2062296..2062472	-	177	Protein_1782	DUF3606 domain-containing protein	-
ATY43_RS09480	2062694..2063095	+	402	WP_011259345.1	H-NS histone family protein	-
ATY43_RS09490	2063959..2064138	-	180	WP_015463309.1	hypothetical protein	-
ATY43_RS24945	2064409..2064663	-	255	WP_198912806.1	hypothetical protein	-
ATY43_RS09500	2064740..2065030	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ATY43_RS09505	2065018..2065296	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
ATY43_RS27220	2065377..2065580	-	204	WP_198912807.1	hypothetical protein	-
ATY43_RS27225	2065492..2065836	-	345	WP_198912817.1	hypothetical protein	-
ATY43_RS24955	2065781..2065981	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
ATY43_RS09510	2066230..2067186	-	957	WP_041182719.1	IS30-like element IS1112b family transposase	-
ATY43_RS09515	2067588..2068556	-	969	WP_012445118.1	IS5-like element ISXo1 family transposase	-
ATY43_RS09520	2068960..2070144	-	1185	WP_011408397.1	IS256 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T59731 WP_027703932.1 NZ_CP013961:c2065030-2064740 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T59731 NZ_CP013961:c2065030-2064740 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT59731 WP_011408759.1 NZ_CP013961:c2065296-2065018 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT59731 NZ_CP013961:c2065296-2065018 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2