Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3961251..3961522 Replicon chromosome
Accession NZ_CP013952
Organism Escherichia coli strain HST04

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3961381..3961484 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3961251..3961522 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AWH44_RS20365 3957806..3958468 - 663 WP_000944256.1 exodeoxyribonuclease X -
AWH44_RS20370 3958492..3959148 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
AWH44_RS20375 3959250..3959480 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AWH44_RS20380 3959619..3959993 + 375 WP_000168747.1 CopC domain-containing protein YobA -
AWH44_RS20385 3959997..3960869 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
AWH44_RS20390 3960882..3961223 + 342 WP_000976476.1 YebY family protein -
- 3961251..3961522 - 272 - - Antitoxin
- 3961381..3961484 + 104 - - Toxin
AWH44_RS20395 3961619..3962275 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
AWH44_RS20400 3962276..3962467 - 192 WP_000457842.1 YebW family protein -
AWH44_RS20405 3962572..3962808 - 237 WP_001295499.1 DUF1480 family protein -
AWH44_RS20410 3962926..3964365 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T59663 NZ_CP013952:3961381-3961484 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT59663 NZ_CP013952:c3961522-3961251 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References