Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4199349..4199890 Replicon chromosome
Accession NZ_CP013923
Organism Achromobacter denitrificans strain USDA-ARS-USMARC-56712

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag APT56_RS18730 Protein ID WP_059273042.1
Coordinates 4199349..4199624 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag APT56_RS18735 Protein ID WP_059271590.1
Coordinates 4199624..4199890 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APT56_RS18710 4195301..4196224 + 924 WP_006385014.1 ABC transporter permease -
APT56_RS18715 4196230..4197096 + 867 WP_049054177.1 ABC transporter permease -
APT56_RS18720 4197154..4198893 + 1740 WP_059271588.1 peptidase M14 -
APT56_RS18725 4198906..4199343 + 438 WP_054415951.1 acetyltransferase -
APT56_RS18730 4199349..4199624 - 276 WP_059273042.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
APT56_RS18735 4199624..4199890 - 267 WP_059271590.1 ribbon-helix-helix domain-containing protein Antitoxin
APT56_RS28635 4200137..4200715 + 579 WP_156430342.1 TonB-dependent receptor -
APT56_RS18740 4200749..4200955 - 207 WP_059271592.1 hypothetical protein -
APT56_RS18745 4200952..4201527 - 576 WP_054415953.1 GNAT family N-acetyltransferase -
APT56_RS18750 4201703..4202338 - 636 WP_059271593.1 class I SAM-dependent methyltransferase -
APT56_RS18755 4202335..4203939 - 1605 WP_059271594.1 lytic murein transglycosylase -
APT56_RS18760 4204038..4204712 - 675 WP_139122240.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10667.39 Da        Isoelectric Point: 10.0857

>T59588 WP_059273042.1 NZ_CP013923:c4199624-4199349 [Achromobacter denitrificans]
MEMKWTSKALSDLARLHEFLAAVNRPAAVRAVQALVKASSVLPTNSRIGEQLFQFEPREVRRILVGEYEIRYEILDSIIY
VLRLWHTRENR

Download         Length: 276 bp

>T59588 NZ_CP013923:c4199624-4199349 [Achromobacter denitrificans]
ATGGAAATGAAGTGGACCAGCAAGGCGCTTTCCGATCTGGCACGCTTGCATGAATTCCTGGCGGCAGTGAATAGGCCTGC
GGCTGTACGGGCTGTGCAAGCGTTGGTCAAGGCTTCAAGTGTTTTGCCGACCAACTCCCGCATTGGCGAGCAGCTATTTC
AGTTCGAACCGCGCGAGGTACGCAGGATATTGGTCGGGGAGTACGAAATACGTTACGAGATCCTGGATTCGATCATCTAC
GTATTGCGACTGTGGCACACCCGGGAGAACCGCTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9713.03 Da        Isoelectric Point: 4.7377

>AT59588 WP_059271590.1 NZ_CP013923:c4199890-4199624 [Achromobacter denitrificans]
MSPATKVLTAHVPLPLAEKVDQMAARLDRSRGWIVKQALSAWIAQEEERDKLTQQALDDVNAGRIVDDQAVQAWAESLGS
DQPLPLPR

Download         Length: 267 bp

>AT59588 NZ_CP013923:c4199890-4199624 [Achromobacter denitrificans]
ATGAGTCCCGCAACCAAGGTGCTGACCGCACATGTGCCGCTTCCGTTGGCCGAGAAGGTCGATCAGATGGCTGCGCGCCT
GGACCGATCTCGCGGCTGGATCGTGAAGCAGGCTCTGTCCGCTTGGATCGCCCAAGAGGAGGAACGTGACAAGCTCACCC
AGCAAGCGCTTGATGACGTGAATGCAGGTCGGATTGTGGATGATCAAGCCGTGCAGGCCTGGGCGGAGAGCCTGGGCTCT
GACCAGCCATTGCCGCTGCCGCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References