Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1979275..1979543 Replicon chromosome
Accession NZ_CP013835
Organism Escherichia coli strain JJ2434

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1979313..1979415 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1979275..1979543 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AVR68_RS11175 1976433..1977872 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AVR68_RS11180 1977989..1978225 + 237 WP_001295499.1 DUF1480 family protein -
AVR68_RS11185 1978330..1978521 + 192 WP_001296140.1 YebW family protein -
AVR68_RS11190 1978522..1979178 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 1979275..1979543 + 269 - - Antitoxin
- 1979313..1979415 - 103 - - Toxin
AVR68_RS11200 1979573..1979914 - 342 WP_000976472.1 YebY family protein -
AVR68_RS11205 1979927..1980799 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
AVR68_RS11210 1980803..1981177 - 375 WP_000168747.1 CopC domain-containing protein YobA -
AVR68_RS11215 1981316..1981546 + 231 WP_000916763.1 DNA polymerase III subunit theta -
AVR68_RS11220 1981648..1982304 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
AVR68_RS11225 1982328..1982990 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T59446 NZ_CP013835:c1979415-1979313 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT59446 NZ_CP013835:1979275-1979543 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References