Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 1293840..1294385 Replicon chromosome
Accession NZ_CP013826
Organism Vibrio parahaemolyticus strain FORC_018

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FORC18_RS06225 Protein ID WP_053047111.1
Coordinates 1293840..1294136 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag FORC18_RS06230 Protein ID WP_053047112.1
Coordinates 1294143..1294385 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC18_RS06185 1288885..1289583 + 699 WP_053047105.1 hypothetical protein -
FORC18_RS24010 1289608..1289754 + 147 WP_082241060.1 DUF3265 domain-containing protein -
FORC18_RS06195 1289777..1290190 + 414 WP_053047106.1 hypothetical protein -
FORC18_RS06200 1290378..1291703 + 1326 WP_053047107.1 SH3 domain-containing protein -
FORC18_RS24875 1291743..1291868 + 126 WP_153884734.1 hypothetical protein -
FORC18_RS06210 1291861..1292499 + 639 WP_071936819.1 hypothetical protein -
FORC18_RS06215 1292613..1293080 + 468 WP_053047825.1 hypothetical protein -
FORC18_RS06225 1293840..1294136 - 297 WP_053047111.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FORC18_RS06230 1294143..1294385 - 243 WP_053047112.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FORC18_RS06235 1294627..1295124 + 498 WP_053047113.1 hypothetical protein -
FORC18_RS06240 1295139..1295231 + 93 WP_071936820.1 DUF3265 domain-containing protein -
FORC18_RS06245 1295261..1295707 + 447 WP_053047114.1 GNAT family N-acetyltransferase -
FORC18_RS06250 1295881..1296183 + 303 WP_053047115.1 hypothetical protein -
FORC18_RS06255 1296198..1296290 + 93 WP_072829088.1 DUF3265 domain-containing protein -
FORC18_RS06260 1296327..1297040 + 714 WP_053047116.1 hypothetical protein -
FORC18_RS06265 1297055..1297147 + 93 WP_071936822.1 DUF3265 domain-containing protein -
FORC18_RS06270 1297249..1298160 + 912 WP_053047117.1 restriction endonuclease -
FORC18_RS06275 1298175..1298267 + 93 WP_071936823.1 DUF3265 domain-containing protein -
FORC18_RS06280 1298303..1298755 + 453 WP_053047119.1 hypothetical protein -
FORC18_RS06285 1298763..1298885 + 123 WP_009705224.1 DUF3265 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1284450..1390555 106105
- inside Integron - - 1284974..1361671 76697


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11275.94 Da        Isoelectric Point: 9.3813

>T59383 WP_053047111.1 NZ_CP013826:c1294136-1293840 [Vibrio parahaemolyticus]
MQKNKYKLSKLAQAHLLKIKNYTVNNFSEMQWRNYKDTLLTGFQMLADNPEVGRSCDDIYPNGFHFPVGKHAAYFTKEDG
FILVVAVLGQSQLPQNHL

Download         Length: 297 bp

>T59383 NZ_CP013826:c1294136-1293840 [Vibrio parahaemolyticus]
ATGCAAAAGAATAAATATAAACTAAGTAAATTAGCTCAGGCTCATTTATTAAAAATCAAAAACTATACCGTTAATAACTT
TTCAGAGATGCAGTGGCGCAACTACAAAGATACGTTACTGACTGGATTTCAGATGCTTGCTGACAATCCGGAAGTTGGTC
GAAGTTGCGATGACATTTACCCAAACGGGTTTCACTTCCCCGTTGGTAAGCACGCAGCTTACTTTACAAAAGAAGACGGC
TTCATTTTGGTTGTAGCTGTACTCGGTCAGTCACAATTACCGCAAAACCACTTATGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8986.22 Da        Isoelectric Point: 5.1131

>AT59383 WP_053047112.1 NZ_CP013826:c1294385-1294143 [Vibrio parahaemolyticus]
MHTLTANDAKRNFGELLLSAQREPVKISKNSKDAVVVMSIKDYEELEAMKADYLKHCFESAKEDLAQGNVVNGEDFLRAL

Download         Length: 243 bp

>AT59383 NZ_CP013826:c1294385-1294143 [Vibrio parahaemolyticus]
ATGCACACATTAACAGCAAATGATGCAAAACGTAATTTTGGTGAGCTTCTTCTGAGCGCACAACGTGAGCCAGTAAAAAT
TAGCAAAAACAGCAAAGATGCCGTAGTTGTAATGTCTATTAAAGATTATGAAGAGCTAGAAGCTATGAAAGCTGATTACC
TTAAACATTGCTTTGAGTCCGCGAAAGAAGACCTAGCGCAAGGCAATGTGGTTAATGGTGAAGACTTCTTGCGCGCCTTG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References