Detailed information of TA system TA059329

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 119935..120466
• Replicon: plasmid p2PS5
• Accession: NZ_CP013780
• Organism: Piscirickettsia salmonis strain PM51819A

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: AVI52_RS18265
• Protein ID: WP_016210662.1
• Coordinates: 120179..120466 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: AVI52_RS18260
• Protein ID: WP_016210670.1
• Coordinates: 119935..120189 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AVI52_RS18250	115415..116554	-	1140	WP_032126910.1	hypothetical protein	-
AVI52_RS18255	116554..119841	-	3288	WP_016210653.1	host specificity protein J	-
AVI52_RS18260	119935..120189	+	255	WP_016210670.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
AVI52_RS18265	120179..120466	+	288	WP_016210662.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AVI52_RS18270	120473..121030	-	558	WP_016210665.1	tail assembly protein	-
AVI52_RS18275	121020..121766	-	747	WP_032126911.1	C40 family peptidase	-
AVI52_RS18280	121735..122406	-	672	WP_016210666.1	phage minor tail protein L	-
AVI52_RS18285	122403..122744	-	342	WP_016210657.1	phage tail protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..122750	122750

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (8-55)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11064.15 Da
• Isoelectric Point: 10.7358

>T59329 WP_016210662.1 NZ_CP013780:120179-120466 [Piscirickettsia salmonis]
MTYKLQFHKEAYKEWKKLNPTTQQQFQKVLKKRLINPHIPSAVCGGDLKGCYKIKLRALGYRLIYTVKEDKVVVQVLAIG
SRNRLEAYRLAASRL

Nucleotide

• Length: 288 bp

>T59329 NZ_CP013780:120179-120466 [Piscirickettsia salmonis]
ATGACTTATAAATTACAATTTCACAAAGAAGCGTATAAAGAGTGGAAAAAACTAAATCCAACAACTCAGCAACAGTTTCA
AAAAGTTTTGAAAAAACGCTTAATTAACCCACATATCCCATCAGCAGTGTGTGGTGGTGATTTAAAAGGCTGCTATAAAA
TTAAATTAAGAGCGCTCGGTTATCGTTTAATTTATACAGTGAAAGAGGATAAAGTGGTTGTTCAAGTCTTGGCGATTGGT
TCCAGAAACCGCTTAGAAGCGTATCGTTTAGCGGCAAGTCGCCTATAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9450.69 Da
• Isoelectric Point: 4.0808

>AT59329 WP_016210670.1 NZ_CP013780:119935-120189 [Piscirickettsia salmonis]
MKQLYAQQSVTITELRKSPTSVINEANGEPVVILNHNAPAAYMVPPELFEAMLDSYEDRQLEGIVKKRLNSPDCDFIDVD
VDDL

Nucleotide

• Length: 255 bp

>AT59329 NZ_CP013780:119935-120189 [Piscirickettsia salmonis]
ATGAAACAGCTCTACGCACAACAGTCGGTAACCATTACAGAACTTAGAAAAAGCCCAACCAGCGTTATTAATGAAGCCAA
CGGCGAGCCGGTGGTTATTTTGAATCATAATGCTCCTGCGGCGTACATGGTGCCACCTGAACTTTTTGAAGCCATGCTCG
ACTCGTATGAAGACCGCCAACTTGAAGGCATAGTCAAAAAACGTTTGAATTCTCCTGATTGTGACTTTATTGATGTCGAT
GTCGATGACTTATAA