Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1531525..1533257 Replicon chromosome
Accession NZ_CP013737
Organism Herbaspirillum rubrisubalbicans M1

Toxin (Protein)


Gene name doc Uniprot ID A0A0U3LV18
Locus tag HRUBRI_RS06530 Protein ID WP_058894744.1
Coordinates 1531525..1532403 (+) Length 293 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag HRUBRI_RS06535 Protein ID WP_026052222.1
Coordinates 1532424..1533257 (+) Length 278 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRUBRI_RS06505 1527395..1528180 + 786 WP_017454058.1 ABC transporter ATP-binding protein -
HRUBRI_RS06510 1528248..1529243 + 996 WP_058894740.1 ABC transporter substrate-binding protein -
HRUBRI_RS06515 1529246..1530109 + 864 WP_058894741.1 ABC transporter permease -
HRUBRI_RS06520 1530151..1530921 + 771 WP_058894742.1 SDR family oxidoreductase -
HRUBRI_RS06525 1530979..1531515 + 537 WP_058894743.1 cupin domain-containing protein -
HRUBRI_RS06530 1531525..1532403 + 879 WP_058894744.1 alpha/beta hydrolase Toxin
HRUBRI_RS06535 1532424..1533257 + 834 WP_026052222.1 IclR family transcriptional regulator Antitoxin
HRUBRI_RS06540 1533259..1534083 + 825 WP_058894745.1 SDR family oxidoreductase -
HRUBRI_RS06545 1534076..1535767 + 1692 WP_058894746.1 thiamine pyrophosphate-binding protein -
HRUBRI_RS06550 1535779..1536579 + 801 WP_017454067.1 aspartate dehydrogenase -
HRUBRI_RS06555 1536605..1538080 + 1476 WP_197416704.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(50-282)

Antitoxin

Transcription regulator IclR, N-terminal

(20-68)


Sequences

Toxin        


Download         Length: 293 a.a.        Molecular weight: 31180.68 Da        Isoelectric Point: 6.8118

>T59239 WP_058894744.1 NZ_CP013737:1531525-1532403 [Herbaspirillum rubrisubalbicans M1]
MPAMNPIVSVNDEQLLHAPLALLEGRFAERSVALPGGQISYRSCGSGPVVVLLHGISSGAASWLRCALELASCARVIAWN
APGYGHSTPLPMSVPKASDYALRLQQMLQALEIEQCVLVGHSLGALMAAAYLACGDGRALSTLLADPALGYGAPGKQQRA
QQVRDERLGALHRLGIPGLAQQPTRLLSDHADAEQHAWVRWNMQWLDAAGYTQAVQLLCGDDIELYLNAAPRRGLSVACG
AEDIVTTPQASEALARQFGLFFHKVHAAGHASYIEQPSQFAALVRAQLTSTY

Download         Length: 879 bp

>T59239 NZ_CP013737:1531525-1532403 [Herbaspirillum rubrisubalbicans M1]
ATGCCTGCCATGAACCCCATCGTTTCGGTCAACGACGAGCAACTCCTGCACGCACCGCTGGCGCTGCTCGAAGGCCGCTT
TGCCGAGCGTAGCGTTGCCCTGCCGGGCGGCCAGATCAGCTATCGCAGTTGCGGCAGCGGGCCGGTGGTGGTGCTCTTGC
ATGGCATCAGTTCGGGCGCGGCCTCCTGGCTGCGCTGCGCCTTGGAGCTGGCCTCCTGCGCCCGGGTGATCGCCTGGAAT
GCGCCGGGCTATGGACATTCCACGCCACTGCCCATGAGCGTGCCCAAGGCCAGCGACTATGCACTGCGCTTGCAGCAGAT
GCTGCAAGCCTTGGAGATCGAGCAATGCGTGCTGGTCGGTCATTCGCTGGGGGCCTTGATGGCCGCCGCTTATCTGGCCT
GCGGCGATGGGCGTGCGCTCAGCACCCTGCTGGCCGATCCGGCCCTGGGTTACGGTGCACCCGGCAAGCAACAGCGGGCG
CAGCAGGTACGCGATGAGCGCCTGGGGGCACTGCACCGGCTGGGTATCCCTGGCCTGGCGCAGCAACCTACGCGCCTGCT
GTCGGACCATGCTGACGCCGAGCAGCACGCCTGGGTGCGCTGGAACATGCAATGGCTGGATGCGGCCGGTTACACCCAGG
CCGTGCAATTGTTGTGCGGCGACGATATCGAGCTCTATCTGAACGCAGCGCCACGGCGGGGACTGTCGGTGGCCTGCGGC
GCGGAAGATATCGTCACCACCCCCCAGGCCAGTGAAGCGCTGGCCCGGCAATTTGGACTTTTCTTTCATAAGGTGCACGC
CGCCGGCCATGCCAGCTATATCGAGCAGCCGTCGCAATTTGCCGCGCTGGTGCGCGCGCAACTCACCTCAACCTACTAA

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 30797.35 Da        Isoelectric Point: 6.5033

>AT59239 WP_026052222.1 NZ_CP013737:1532424-1533257 [Herbaspirillum rubrisubalbicans M1]
MSKPVMPEEESQDKYSVPGLERGLRLLCEFSRQDKTLSAPELARRLDIPRSTVFRLLATLERMGFVERADGGRDYRLGMS
VLRLGFEYLASLELTEIGRPLLDRLRDEIGYSCNLVVRDGRSIVYVAKSVTQTAFTSHVNVGTRLPAHATVLGRVLLEDL
SLPQLRALYPEQHLEVFSSNTPKTVVELFDMVQADKERGFVLQEGFFETSISTVAAPVRDHSGLVVAALGATIPSPHIDA
SQLDVIVARVRETAAELSRLLDHAPERGAKVVNMWRG

Download         Length: 834 bp

>AT59239 NZ_CP013737:1532424-1533257 [Herbaspirillum rubrisubalbicans M1]
ATGAGCAAACCTGTGATGCCAGAAGAAGAATCGCAAGACAAGTATTCCGTCCCCGGCCTGGAACGTGGCCTGCGCCTGCT
GTGCGAATTCAGCCGTCAGGACAAGACGCTGTCGGCCCCCGAACTGGCGCGTCGCCTGGATATCCCGCGCTCCACCGTGT
TTCGCCTGCTGGCCACGCTGGAACGCATGGGTTTCGTCGAGCGTGCCGATGGCGGACGTGACTACCGCCTGGGCATGTCG
GTGCTGCGCCTGGGCTTCGAATACCTGGCTTCGCTGGAATTGACCGAGATCGGCCGTCCGCTGCTGGACCGCCTGCGCGA
TGAGATCGGCTATTCCTGCAATCTGGTGGTACGCGATGGCCGCTCCATCGTCTATGTCGCCAAGTCGGTCACCCAGACCG
CCTTCACCAGCCACGTCAACGTCGGCACCCGCCTGCCGGCGCACGCCACTGTGCTGGGCCGCGTGCTGCTGGAAGACCTG
AGCCTGCCGCAACTGCGCGCGCTGTATCCCGAACAGCACCTGGAAGTCTTCTCCAGCAATACCCCCAAGACCGTGGTCGA
ACTGTTCGACATGGTGCAGGCCGACAAGGAGCGCGGTTTCGTGTTGCAGGAAGGTTTCTTCGAAACCAGCATCTCCACCG
TGGCCGCGCCGGTGCGCGATCACTCCGGCCTGGTGGTGGCTGCGCTGGGGGCGACGATTCCTTCGCCGCACATCGATGCC
AGCCAGCTCGACGTGATCGTGGCGCGTGTGCGCGAGACCGCGGCCGAACTGTCCCGCCTGCTGGACCACGCCCCCGAACG
TGGCGCCAAGGTGGTCAACATGTGGCGGGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0U3LV18

Antitoxin

Source ID Structure

References