Detailed information of TA system TA059238

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): virAT/YafQ(toxin)
• Location: 30568..31111
• Replicon: plasmid pOR12Vir
• Accession: NZ_CP013734
• Organism: Campylobacter coli strain OR12

Toxin (Protein)

• Gene name: virT
• Uniprot ID: -
• Locus tag: ATE51_RS11095
• Protein ID: WP_053868684.1
• Coordinates: 30842..31111 (+)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: virA
• Uniprot ID: -
• Locus tag: ATE51_RS11090
• Protein ID: WP_058914785.1
• Coordinates: 30568..30852 (+)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ATE51_RS11050 (ATE51_05038)	26701..27129	+	429	WP_058914780.1	hypothetical protein	-
ATE51_RS11055 (ATE51_05039)	27600..27944	+	345	WP_024266121.1	hypothetical protein	-
ATE51_RS11060 (ATE51_05040)	27958..28263	+	306	WP_058914781.1	hypothetical protein	-
ATE51_RS11065 (ATE51_05041)	28275..28493	+	219	WP_058914782.1	hypothetical protein	-
ATE51_RS11070 (ATE51_05042)	28556..28990	+	435	WP_058914783.1	hypothetical protein	-
ATE51_RS11075 (ATE51_05043)	28977..29408	+	432	WP_058914784.1	hypothetical protein	-
ATE51_RS11080 (ATE51_05044)	29616..29801	+	186	WP_004306057.1	hypothetical protein	-
ATE51_RS11085 (ATE51_05045)	29973..30344	+	372	WP_052835040.1	hypothetical protein	-
ATE51_RS11090 (ATE51_05046)	30568..30852	+	285	WP_058914785.1	hypothetical protein	Antitoxin
ATE51_RS11095 (ATE51_05047)	30842..31111	+	270	WP_053868684.1	type II toxin-antitoxin system YafQ family toxin	Toxin
ATE51_RS11100 (ATE51_05048)	31236..31547	+	312	Protein_43	hypothetical protein	-
ATE51_RS11105 (ATE51_05049)	31855..33426	-	1572	WP_043012966.1	relaxase/mobilization nuclease domain-containing protein	-
ATE51_RS11110 (ATE51_05050)	34248..34550	+	303	WP_058914787.1	hypothetical protein	-
ATE51_RS11115 (ATE51_05051)	34550..34792	+	243	WP_052835045.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	virB8 / virB9 / virB10 / virB11 / virD4 / virB4 / Cjp54	1..37395	37395

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (3-89)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10616.28 Da
• Isoelectric Point: 9.5064

>T59238 WP_053868684.1 NZ_CP013734:30842-31111 [Campylobacter coli]
MPYKITLSKKYKQKYKKANTKDRILIDEVVEKLSNDETLEEKYKDHALKGNYIGFRECHIKPDLLLVYRKNNDILELYLA
NLGNHNNIF

Nucleotide

• Length: 270 bp

>T59238 NZ_CP013734:30842-31111 [Campylobacter coli]
ATGCCTTATAAAATTACATTATCTAAAAAATACAAGCAAAAATATAAAAAAGCAAACACAAAAGACAGAATATTGATTGA
TGAAGTTGTTGAAAAATTATCTAATGATGAAACATTAGAAGAAAAATACAAAGACCACGCATTAAAAGGAAATTATATTG
GTTTTAGAGAATGCCACATTAAACCTGATTTGTTATTAGTCTATCGCAAAAATAATGATATTTTAGAATTATATTTGGCT
AATTTAGGAAATCACAATAATATTTTTTAG

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 11187.70 Da
• Isoelectric Point: 9.7619

>AT59238 WP_058914785.1 NZ_CP013734:30568-30852 [Campylobacter coli]
MFDYSKYENASEKQLIHALTLAEKRAEKLNSQLKENNEFFKFLQKKLKKSFNAKKTKKAEQRRPELDEAIEDYKNGNVET
YANFEEYKKAMNAL

Nucleotide

• Length: 285 bp

>AT59238 NZ_CP013734:30568-30852 [Campylobacter coli]
ATGTTTGATTATTCTAAATATGAAAATGCTAGCGAAAAACAATTAATACACGCTTTGACTTTAGCAGAAAAAAGGGCGGA
GAAACTAAACTCGCAATTAAAAGAGAATAATGAATTTTTTAAATTTTTACAAAAAAAGTTAAAAAAATCTTTTAACGCCA
AAAAAACAAAAAAAGCAGAGCAAAGAAGACCTGAATTAGATGAAGCGATTGAAGATTATAAAAATGGAAATGTAGAAACC
TATGCTAATTTTGAAGAATATAAAAAGGCTATGAATGCCTTATAA