Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3268531..3268676 Replicon chromosome
Accession NZ_CP013711
Organism Klebsiella pneumoniae strain J1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3268567..3268669 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3268531..3268676 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AU361_RS16210 3263661..3265721 + 2061 WP_004151449.1 oligopeptidase B -
AU361_RS16215 3265725..3266384 - 660 WP_002911407.1 exodeoxyribonuclease X -
AU361_RS16220 3266463..3266693 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AU361_RS16225 3266806..3267180 + 375 WP_023286640.1 CopC domain-containing protein YobA -
AU361_RS16230 3267184..3268053 + 870 WP_023286639.1 copper homeostasis membrane protein CopD -
AU361_RS16235 3268070..3268408 + 339 WP_016529031.1 YebY family protein -
- 3268531..3268676 - 146 - - Antitoxin
- 3268567..3268669 + 103 - - Toxin
AU361_RS29070 3269043..3269186 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
AU361_RS16245 3269291..3270259 - 969 WP_074194451.1 VirK/YbjX family protein -
AU361_RS16250 3270416..3271069 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
AU361_RS16255 3271066..3271257 - 192 WP_002911395.1 YebW family protein -
AU361_RS16260 3271355..3271594 - 240 WP_002911393.1 YebV family protein -
AU361_RS16265 3271710..3273143 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T59215 NZ_CP013711:3268567-3268669 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT59215 NZ_CP013711:c3268676-3268531 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References