Detailed information of TA system TA059199

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2895149..2895705
• Replicon: chromosome
• Accession: NZ_CP013679
• Organism: Xanthomonas oryzae pv. oryzae strain PXO602

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: ATY49_RS13715
• Protein ID: WP_027703932.1
• Coordinates: 2895149..2895439 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: ATY49_RS13720
• Protein ID: WP_011408759.1
• Coordinates: 2895427..2895705 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ATY49_RS13680	2890919..2892010	+	1092	WP_041182166.1	ribonuclease D	-
ATY49_RS13685	2892086..2892423	-	338	Protein_2585	ATP-dependent DNA ligase	-
ATY49_RS27225	2892483..2892689	-	207	Protein_2586	hypothetical protein	-
ATY49_RS24920	2892705..2892881	-	177	Protein_2587	DUF3606 domain-containing protein	-
ATY49_RS13695	2893103..2893504	+	402	WP_011259345.1	H-NS histone family protein	-
ATY49_RS24925	2893829..2894033	-	205	Protein_2589	kfra protein	-
ATY49_RS13705	2894368..2894547	-	180	WP_015463309.1	hypothetical protein	-
ATY49_RS27230	2894691..2894888	-	198	WP_004541336.1	hypothetical protein	-
ATY49_RS13715	2895149..2895439	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ATY49_RS13720	2895427..2895705	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
ATY49_RS24935	2895786..2896218	-	433	Protein_2594	relaxase	-
ATY49_RS24940	2896190..2896390	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
ATY49_RS13725	2897151..2898335	-	1185	WP_011408397.1	IS256 family transposase	-
ATY49_RS13730	2898916..2899881	+	966	Protein_2597	IS1595-like element ISXo5 family transposase	-
ATY49_RS24945	2899983..2900588	+	606	Protein_2598	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T59199 WP_027703932.1 NZ_CP013679:c2895439-2895149 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T59199 NZ_CP013679:c2895439-2895149 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT59199 WP_011408759.1 NZ_CP013679:c2895705-2895427 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT59199 NZ_CP013679:c2895705-2895427 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2