Detailed information of TA system TA059195

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2866390..2866946
• Replicon: chromosome
• Accession: NZ_CP013678
• Organism: Xanthomonas oryzae pv. oryzae strain PXO563

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: ATY48_RS13700
• Protein ID: WP_027703932.1
• Coordinates: 2866390..2866680 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: ATY48_RS13705
• Protein ID: WP_011408759.1
• Coordinates: 2866668..2866946 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ATY48_RS13665	2862160..2863251	+	1092	WP_041182166.1	ribonuclease D	-
ATY48_RS13670	2863327..2863664	-	338	Protein_2571	ATP-dependent DNA ligase	-
ATY48_RS27235	2863724..2863930	-	207	Protein_2572	hypothetical protein	-
ATY48_RS24900	2863946..2864122	-	177	Protein_2573	DUF3606 domain-containing protein	-
ATY48_RS13680	2864344..2864745	+	402	WP_011259345.1	H-NS histone family protein	-
ATY48_RS24905	2865070..2865274	-	205	Protein_2575	kfra protein	-
ATY48_RS13690	2865609..2865788	-	180	WP_015463309.1	hypothetical protein	-
ATY48_RS27240	2865932..2866129	-	198	WP_004541336.1	hypothetical protein	-
ATY48_RS13700	2866390..2866680	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ATY48_RS13705	2866668..2866946	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
ATY48_RS24920	2867027..2867459	-	433	Protein_2580	relaxase	-
ATY48_RS24925	2867431..2867631	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
ATY48_RS13710	2868392..2869576	-	1185	WP_011408522.1	IS256 family transposase	-
ATY48_RS13715	2870157..2871122	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
ATY48_RS24930	2871224..2871829	+	606	Protein_2584	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T59195 WP_027703932.1 NZ_CP013678:c2866680-2866390 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T59195 NZ_CP013678:c2866680-2866390 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT59195 WP_011408759.1 NZ_CP013678:c2866946-2866668 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT59195 NZ_CP013678:c2866946-2866668 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2