Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 421676..422026 Replicon chromosome
Accession NZ_CP013678
Organism Xanthomonas oryzae pv. oryzae strain PXO563

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag ATY48_RS01995 Protein ID WP_011257368.1
Coordinates 421892..422026 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag ATY48_RS01990 Protein ID WP_011407410.1
Coordinates 421676..421828 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ATY48_RS01965 417956..418639 - 684 WP_011257363.1 dTMP kinase -
ATY48_RS01970 419119..419415 - 297 WP_012446308.1 hypothetical protein -
ATY48_RS01975 419422..419661 - 240 WP_011257365.1 hypothetical protein -
ATY48_RS01980 419658..420323 - 666 WP_069959695.1 hypothetical protein -
ATY48_RS01985 420645..421568 + 924 WP_011407409.1 arginase -
ATY48_RS01990 421676..421828 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
ATY48_RS01995 421892..422026 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
ATY48_RS02000 422267..422476 + 210 WP_011407411.1 CsbD family protein -
ATY48_RS02005 422645..423934 + 1290 WP_069959696.1 tryptophan--tRNA ligase -
ATY48_RS02010 423987..425009 + 1023 WP_075240574.1 MBL fold metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T59194 WP_011257368.1 NZ_CP013678:421892-422026 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T59194 NZ_CP013678:421892-422026 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT59194 WP_011407410.1 NZ_CP013678:421676-421828 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT59194 NZ_CP013678:421676-421828 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References