Detailed information of TA system TA059191

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2913003..2913559
• Replicon: chromosome
• Accession: NZ_CP013677
• Organism: Xanthomonas oryzae pv. oryzae strain PXO524

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: ATY47_RS13895
• Protein ID: WP_027703932.1
• Coordinates: 2913003..2913293 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: ATY47_RS13900
• Protein ID: WP_011408759.1
• Coordinates: 2913281..2913559 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ATY47_RS13860	2908773..2909864	+	1092	WP_041182166.1	ribonuclease D	-
ATY47_RS13865	2909940..2910277	-	338	Protein_2619	ATP-dependent DNA ligase	-
ATY47_RS27305	2910337..2910543	-	207	Protein_2620	hypothetical protein	-
ATY47_RS25030	2910559..2910735	-	177	Protein_2621	DUF3606 domain-containing protein	-
ATY47_RS13875	2910957..2911358	+	402	WP_011259345.1	H-NS histone family protein	-
ATY47_RS25035	2911683..2911887	-	205	Protein_2623	kfra protein	-
ATY47_RS13885	2912222..2912401	-	180	WP_015463309.1	hypothetical protein	-
ATY47_RS26705	2912545..2912742	-	198	WP_004541336.1	hypothetical protein	-
ATY47_RS13895	2913003..2913293	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ATY47_RS13900	2913281..2913559	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
ATY47_RS25045	2913640..2914072	-	433	Protein_2628	relaxase	-
ATY47_RS25050	2914044..2914244	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
ATY47_RS13905	2915005..2916189	-	1185	WP_011408397.1	IS256 family transposase	-
ATY47_RS13910	2916770..2917735	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
ATY47_RS25055	2917837..2918442	+	606	Protein_2632	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T59191 WP_027703932.1 NZ_CP013677:c2913293-2913003 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T59191 NZ_CP013677:c2913293-2913003 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT59191 WP_011408759.1 NZ_CP013677:c2913559-2913281 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT59191 NZ_CP013677:c2913559-2913281 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2