Detailed information of TA system TA059187

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2921013..2921569
• Replicon: chromosome
• Accession: NZ_CP013676
• Organism: Xanthomonas oryzae pv. oryzae strain PXO282

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: ATY46_RS13980
• Protein ID: WP_229001948.1
• Coordinates: 2921013..2921264 (-)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: ATY46_RS13985
• Protein ID: WP_011408759.1
• Coordinates: 2921291..2921569 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ATY46_RS13945 (ATY46_13525)	2916783..2917874	+	1092	WP_041182166.1	ribonuclease D	-
ATY46_RS13950 (ATY46_13530)	2917950..2918287	-	338	Protein_2658	ATP-dependent DNA ligase	-
ATY46_RS25180	2918569..2918745	-	177	Protein_2659	DUF3606 domain-containing protein	-
ATY46_RS13960 (ATY46_13540)	2918967..2919368	+	402	WP_011259345.1	H-NS family nucleoid-associated regulatory protein	-
ATY46_RS28400	2919799..2919927	-	129	WP_012444694.1	hypothetical protein	-
ATY46_RS28040	2919896..2920015	-	120	Protein_2662	IS3 family transposase	-
ATY46_RS13970 (ATY46_13550)	2920232..2920486	-	255	WP_223293127.1	hypothetical protein	-
ATY46_RS27500 (ATY46_13555)	2920555..2920752	-	198	WP_004541336.1	hypothetical protein	-
ATY46_RS13980 (ATY46_13560)	2921013..2921264	-	252	WP_229001948.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ATY46_RS13985 (ATY46_13565)	2921291..2921569	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
ATY46_RS25195	2921765..2922109	-	345	WP_199285675.1	hypothetical protein	-
ATY46_RS13990 (ATY46_13570)	2923014..2924198	-	1185	WP_011408397.1	IS256-like element IS1113 family transposase	-
ATY46_RS13995 (ATY46_13575)	2924779..2925744	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
ATY46_RS25205	2925894..2926451	+	558	WP_011259349.1	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-81)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9603.92 Da
• Isoelectric Point: 9.9718

>T59187 WP_229001948.1 NZ_CP013676:c2921264-2921013 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Nucleotide

• Length: 252 bp

>T59187 NZ_CP013676:c2921264-2921013 [Xanthomonas oryzae pv. oryzae]
ATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGATGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGT
CCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAGAAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATT
TTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGGGATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAA
GCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT59187 WP_011408759.1 NZ_CP013676:c2921569-2921291 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT59187 NZ_CP013676:c2921569-2921291 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2