Detailed information of TA system TA059186

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 1085324..1086069
• Replicon: chromosome
• Accession: NZ_CP013676
• Organism: Xanthomonas oryzae pv. oryzae strain PXO282

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: ATY46_RS05270
• Protein ID: WP_199285672.1
• Coordinates: 1085740..1086069 (-)
• Length: 110 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: -
• Locus tag: ATY46_RS05265
• Protein ID: WP_011407754.1
• Coordinates: 1085324..1085743 (-)
• Length: 140 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ATY46_RS26430 (ATY46_05065)	1081612..1081938	-	327	Protein_987	hypothetical protein	-
ATY46_RS05250 (ATY46_05070)	1082240..1083475	+	1236	WP_011257570.1	ISL3-like element ISXoo13 family transposase	-
ATY46_RS05255 (ATY46_05075)	1083513..1084169	-	657	WP_075246166.1	phosphate phosphatase	-
ATY46_RS05260 (ATY46_05080)	1084304..1085272	-	969	WP_011258802.1	IS5-like element ISXo1 family transposase	-
ATY46_RS05265 (ATY46_05085)	1085324..1085743	-	420	WP_011407754.1	macro domain-containing protein	Antitoxin
ATY46_RS05270 (ATY46_05090)	1085740..1086069	-	330	WP_199285672.1	DUF4433 domain-containing protein	Toxin
ATY46_RS05275 (ATY46_05095)	1086172..1087491	+	1320	WP_155296575.1	IS701-like element ISXo15 family transposase	-
ATY46_RS24315	1087535..1087870	-	336	WP_011407757.1	DarT ssDNA thymidine ADP-ribosyltransferase family protein	-
ATY46_RS05280 (ATY46_05100)	1088202..1089128	-	927	WP_011257932.1	Grx4 family monothiol glutaredoxin	-
ATY46_RS05285 (ATY46_05105)	1089174..1089965	+	792	WP_011407758.1	polysaccharide deacetylase family protein	-
ATY46_RS05295 (ATY46_05110)	1090267..1090938	-	672	WP_011407759.1	class I SAM-dependent methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	1082240..1087491	5251

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (3-108)

Antitoxin

• Macro domain (18-130)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 13145.86 Da
• Isoelectric Point: 7.1160

>T59186 WP_199285672.1 NZ_CP013676:c1086069-1085740 [Xanthomonas oryzae pv. oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Nucleotide

• Length: 330 bp

>T59186 NZ_CP013676:c1086069-1085740 [Xanthomonas oryzae pv. oryzae]
TTGCATCATGTCGCCGAACGCCGATGGCCGTTTCTGTTTACTGACAGCCACGCCTACTGCCAGTTGGCGAGCTTCTATTC
CGATTTATCTGATCTCGACAAGATCGACTGGCCGTTGCTCCAAGCACGCGATTTCCGGCGCGACCCAGACGACCCAGCCA
AGTTCGAGCGCTATCAGGCCGAGGCCCTGATTCACCGACACTTGCCGCTTGATGGCCTGCGCGGCATTGTGTGTCATACG
GATGGTTTGAAACAGACCATCGAGCGGCAACTCCAAGAGCGAAACCTGAAATTGCCGGTTCATACCCGCACCGATTGGTA
TTTCCGATGA

Antitoxin

Protein

• Length: 140 a.a.
• Molecular weight: 15607.02 Da
• Isoelectric Point: 6.4733

>AT59186 WP_011407754.1 NZ_CP013676:c1085743-1085324 [Xanthomonas oryzae pv. oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Nucleotide

• Length: 420 bp

>AT59186 NZ_CP013676:c1085743-1085324 [Xanthomonas oryzae pv. oryzae]
ATGATCACGTTTACACAAGGCAATCTACTGGAGTCTGGCGCAGAGGCGCTGGTCAACACCGTCAACACCGTCGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGCTTCAAGGAGAACTTCCTCCGATATGCCGCCGCCTGCAAAGACAACC
AAGTGCGCATTGGCAAAATTTTCGTCACCGAAGTCAACGAACTGGACGGGCCACGCTGGATCATCAATTTTCCGACCAAA
CAGCACTGGCGTGGCGATTCCCGCATCGAATGGATCACTGAAGGATTGCAGGACTTGCACCGTTTTCTGATCGAGAACAA
AGTCAAATCCATTGCCATCCCGCCACTGGGCGCGGGCAATGGAGGATTGGACTGGGCCGAGGTGCGCCCACTGATCGAAG
AAGTACTAGGGAACCTCTGA