59185

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 427077..427427 Replicon chromosome
Accession NZ_CP013676
Organism Xanthomonas oryzae pv. oryzae strain PXO282

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag ATY46_RS02025 Protein ID WP_011257368.1
Coordinates 427293..427427 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag ATY46_RS02020 Protein ID WP_011407410.1
Coordinates 427077..427229 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ATY46_RS01995 (ATY46_01920) 423357..424040 - 684 WP_011257363.1 dTMP kinase -
ATY46_RS27610 424520..425062 - 543 Protein_383 GTPase -
ATY46_RS02010 (ATY46_01935) 425059..425514 - 456 Protein_384 hypothetical protein -
ATY46_RS27615 425506..425724 - 219 Protein_385 hypothetical protein -
ATY46_RS02015 (ATY46_01940) 426046..426969 + 924 WP_011407409.1 arginase -
ATY46_RS02020 (ATY46_01945) 427077..427229 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
ATY46_RS02025 (ATY46_01950) 427293..427427 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
ATY46_RS02030 (ATY46_01955) 427668..427877 + 210 WP_011407411.1 CsbD family protein -
ATY46_RS02035 (ATY46_01960) 428046..429335 + 1290 WP_069959696.1 tryptophan--tRNA ligase -
ATY46_RS02040 (ATY46_01965) 429466..430410 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T59185 WP_011257368.1 NZ_CP013676:427293-427427 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T59185 NZ_CP013676:427293-427427 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT59185 WP_011407410.1 NZ_CP013676:427077-427229 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT59185 NZ_CP013676:427077-427229 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References