59184

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4675515..4675865 Replicon chromosome
Accession NZ_CP013675
Organism Xanthomonas oryzae pv. oryzae strain PXO236

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag ATY45_RS22005 Protein ID WP_011257368.1
Coordinates 4675515..4675649 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag ATY45_RS22010 Protein ID WP_011407410.1
Coordinates 4675713..4675865 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ATY45_RS21990 4672529..4673551 - 1023 WP_075240574.1 MBL fold metallo-hydrolase -
ATY45_RS21995 4673604..4674893 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
ATY45_RS22000 4675062..4675271 - 210 WP_011407411.1 CsbD family protein -
ATY45_RS22005 4675515..4675649 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
ATY45_RS22010 4675713..4675865 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
ATY45_RS22015 4675973..4676896 - 924 WP_011407409.1 arginase -
ATY45_RS22020 4677218..4677892 + 675 WP_011257366.1 hypothetical protein -
ATY45_RS22025 4677889..4678128 + 240 WP_011257365.1 hypothetical protein -
ATY45_RS22030 4678135..4678431 + 297 WP_011257364.1 hypothetical protein -
ATY45_RS22035 4678911..4679594 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T59184 WP_011257368.1 NZ_CP013675:c4675649-4675515 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T59184 NZ_CP013675:c4675649-4675515 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT59184 WP_011407410.1 NZ_CP013675:c4675865-4675713 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT59184 NZ_CP013675:c4675865-4675713 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References