Detailed information of TA system TA059183

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2079122..2079678
• Replicon: chromosome
• Accession: NZ_CP013675
• Organism: Xanthomonas oryzae pv. oryzae strain PXO236

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: ATY45_RS09805
• Protein ID: WP_027703932.1
• Coordinates: 2079388..2079678 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: ATY45_RS09800
• Protein ID: WP_011408759.1
• Coordinates: 2079122..2079400 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ATY45_RS09785	2074393..2075712	+	1320	WP_155296443.1	IS701 family transposase	-
ATY45_RS09790	2075862..2076830	+	969	WP_012445118.1	IS5-like element ISXo1 family transposase	-
ATY45_RS09795	2077232..2078188	+	957	WP_041182545.1	IS30-like element IS1112b family transposase	-
ATY45_RS24500	2078437..2078637	+	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
ATY45_RS24505	2078609..2079041	+	433	Protein_1843	relaxase	-
ATY45_RS09800	2079122..2079400	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
ATY45_RS09805	2079388..2079678	+	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ATY45_RS24510	2079681..2080009	+	329	Protein_1846	hypothetical protein	-
ATY45_RS09815	2080280..2080459	+	180	WP_015463309.1	hypothetical protein	-
ATY45_RS24515	2080794..2080998	+	205	Protein_1848	kfra protein	-
ATY45_RS09825	2081323..2081724	-	402	WP_011259345.1	H-NS histone family protein	-
ATY45_RS24520	2081946..2082122	+	177	Protein_1850	DUF3606 domain-containing protein	-
ATY45_RS26955	2082138..2082344	+	207	Protein_1851	hypothetical protein	-
ATY45_RS09835	2082404..2082720	+	317	Protein_1852	ATP-dependent DNA ligase	-
ATY45_RS09840	2082817..2083908	-	1092	WP_011408756.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T59183 WP_027703932.1 NZ_CP013675:2079388-2079678 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T59183 NZ_CP013675:2079388-2079678 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT59183 WP_011408759.1 NZ_CP013675:2079122-2079400 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT59183 NZ_CP013675:2079122-2079400 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2