Detailed information of TA system TA059179

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2113834..2114390
• Replicon: chromosome
• Accession: NZ_CP013674
• Organism: Xanthomonas oryzae pv. oryzae strain PXO211

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: ATY44_RS10015
• Protein ID: WP_027703932.1
• Coordinates: 2114100..2114390 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: ATY44_RS10010
• Protein ID: WP_011408759.1
• Coordinates: 2113834..2114112 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ATY44_RS09995	2108986..2110170	+	1185	WP_011408397.1	IS256 family transposase	-
ATY44_RS10000	2110574..2111542	+	969	WP_012445118.1	IS5-like element ISXo1 family transposase	-
ATY44_RS10005	2111944..2112900	+	957	WP_041182719.1	IS30-like element IS1112b family transposase	-
ATY44_RS24890	2113149..2113349	+	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
ATY44_RS24895	2113321..2113753	+	433	Protein_1889	relaxase	-
ATY44_RS10010	2113834..2114112	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
ATY44_RS10015	2114100..2114390	+	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ATY44_RS26635	2114651..2114848	+	198	WP_153296741.1	hypothetical protein	-
ATY44_RS10025	2114992..2115171	+	180	WP_015463309.1	hypothetical protein	-
ATY44_RS24905	2115506..2115710	+	205	Protein_1894	kfra protein	-
ATY44_RS10035	2116035..2116436	-	402	WP_011259345.1	H-NS histone family protein	-
ATY44_RS24910	2116658..2116834	+	177	Protein_1896	DUF3606 domain-containing protein	-
ATY44_RS27430	2116850..2117056	+	207	Protein_1897	hypothetical protein	-
ATY44_RS10045	2117116..2117432	+	317	Protein_1898	ATP-dependent DNA ligase	-
ATY44_RS10050	2117529..2118620	-	1092	WP_011408756.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T59179 WP_027703932.1 NZ_CP013674:2114100-2114390 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T59179 NZ_CP013674:2114100-2114390 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT59179 WP_011408759.1 NZ_CP013674:2113834-2114112 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT59179 NZ_CP013674:2113834-2114112 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2